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Autosomal optic atrophy (AOA) is a form of hereditary optic neuropathy characterized by the irreversible and progressive degermation of the retinal ganglion cells. Most cases of AOA are associated with a single dominant mutation in OPA1, which encodes a protein required for fusion of the inner mitoc...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2025-05-07 | PXD059584 | Pride
Autosomal optic atrophy (AOA) is a form of hereditary optic neuropathy characterized by the irreversible and progressive degermation of the retinal ganglion cells. Most cases of AOA are associated with a single dominant mutation in OPA1, which encodes a protein required for fusion of the inner mitoc...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2025-05-07 | PXD059645 | Pride
To scrutinize the proteomic changes that occur in human temporal lobe epilepsy, we compare peptides present in tissue from sclerotic and non-sclerotic temporal lobe epilepsy resected hippocampi and from non-epilepsy autopsy control tissue
ORGANISM(S): Homo sapiens (Human) 
2025-07-28 | PXD064519 | Pride
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