Glioma stem cell

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Unknown (1468)
Transcriptomics (1329)
Genomics (529)
Proteomics (51)
Methylation profiling (14)
Other (11)
Metabolomics (6)
Genomic (2)

Organisms

Homo sapiens (1030)
Mus musculus (379)
Rattus norvegicus (37)
Danio rerio (15)
Daphnia magna (9)
Sus scrofa (8)
Arabidopsis thaliana (8)
synthetic construct (6)
Macaca fascicularis (3)
Caenorhabditis elegans (3)
Lemna minor (2)
Pimephales promelas (2)
Dictyostelium discoideum (2)
Macaca mulatta (2)
Zea mays (2)
Bos taurus (2)
Nostoc sp. PCC 7120 = FACHB-418 (1)
marine sediment metagenome (1)
Nitrosomonas europaea (1)
Pasteurella multocida (1)
Micropterus salmoides (1)
uncultured bacterium (1)
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Schizosaccharomyces pombe 972h- (1)
Selaginella moellendorffii (1)
Chlorocebus sabaeus (1)
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Oryza sativa (1)
Rattus rattus (1)
Staphylococcus aureus (1)

Organisms

Homo sapiens (252)
Mus musculus (67)
Schmidtea mediterranea (1)
Cervus nippon (1)
Canis lupus (1)
synthetic construct (1)
Rattus norvegicus (1)

Repository

biostudies-arrayexpress (1207)
ENA (372)
geo (272)
pride (43)
EGA (36)
MetaboLights (6)
jPOST (3)
ExpressionAtlas (2)
dbGaP (2)
MassIVE (2)
PanoramaPublic (2)
PeptideAtlas (1)

Tissue

Cell culture (16)
Stem cell (14)
Brain (10)
Cell suspension culture (5)
Permanent cell line cell (3)
HEK-293T cell (2)
Neuronal stem cell (2)
Others (1)
Dendritic cell (1)
Flp-In-T-REx cell (1)
Glioblastoma cell (1)
Glioma cell (1)
LN-229 cell (1)
Neural cell (1)
Subventricular zone (1)

Disease

Glioblastoma (17)
Brain glioblastoma multiforme (13)
Normal (9)
Brain cancer (8)
Glioblastoma multiforme (5)
Central nervous system cancer (2)
Brain glioma (2)
Astrocytoma (1)
Neuroendocrine tumor (1)
Retinoblastoma (1)
Integrated HPV16 only (1)
High grade glioblastoma (1)
Dermal neurofibroma (1)
Malignant glioma (1)
Ependymoma (1)
Oligodendroglioma (1)
Glioma (1)
Liposarcoma (1)
Giant cell glioblastoma (1)
Pilocytic astrocytoma (1)
Giant Cell Glioblastoma (1)
Cervical carcinoma (1)
Temporal lobe epilepsy (1)
Astrocytoma III (1)
Angiosarcoma (1)
Osteosarcoma (1)
Prostate carcinoma (1)
Adenocarcinoma (1)
Cervical cancer (1)
Brain stem glioma (1)

Technology Type

Mass Spectrometry (43)
Shotgun proteomics (18)
Bottom-up proteomics (12)
Affinity purification coupled with mass spectrometry proteomics (9)
Mass spectrometry (4)
ILLUMINA, Illumina HiSeq 2000 (3)
Data-dependent acquisition (3)
Mass spectrometry assay (2)
Data-independent acquisition (2)
SWATH MS (2)
Top-down proteomics (2)
Illumina_Infinium_HumanMethylation450, Illumina_HumanHT-12v4 (1)
Illumina Genome Analyzer IIx, Illumina HiSeq 2000 (1)
Illumina HiSeq 2500 (1)
ILLUMINA, Illumina HiSeq 2000 (ILLUMINA), Illumina HiSeq 2000 (1)
Gel-based experiment (1)
MSE (1)
Mass spectrometry imaging (1)

Instrument Platform

Illumina NovaSeq 6000 (34)
Illumina HiSeq 4000 (33)
NextSeq 500 (19)
Illumina HiSeq 2500 (16)
Illumina HiSeq 2000 (14)
Illumina iScan (5)
Illumina MiSeq (4)
IScan (3)
Illumina NovaSeq X (3)
Ion Torrent Proton (3)
Illumina HiSeq 1500 (3)
NextSeq 550 (3)
Illumina Hybridisation Oven (2)
AB SOLiD 4 System (2)
Illumina Genome Analyzer IIx (2)
DNA Microarray Scanner BA [Agilent Technologies] (2)
Illumina Genome Analyzer II (2)
NextSeq 1000 (2)
NextSeq 2000 (2)
Agilent SureScan Microarray Scanner G2600D (1)
NEBNext rRNA Depletion Kit v2 and NEBNext Ultra II Directional RNA Library Prep Kit Illumina kits (1)
Deeptools, macs3 (1)
Python (1)
Nugen Ovation SPIA; Wafergen’s Apollo liquid handler; KAPA Hyper Prep Library Kit (1)
QIAGEN TissueLyser II (1)
Isoflurane euthanasia chamber (1)
CytoFLEX SRT Benchtop Cell Sorter (1)
Sony SH800S Cell Sorter (1)
Illumins Hybridisation Oven (1)
Raven (Wales High-performance computing cluster) (1)

Publication Date

2013 (179)
2015 (147)
2011 (133)
2010 (130)
2014 (124)
2012 (120)
2016 (106)
2025 (62)
2008 (61)
2022 (59)
2026 (55)
2021 (54)
2009 (50)
2024 (47)
2019 (44)
2020 (42)
2018 (37)
2023 (34)
2017 (25)
2007 (14)
2006 (11)
2005 (2)

UNIPROT ID/AC

A0A024R563 (1)
A0A024R8H9 (1)
A0A024RAN2 (1)
A0A024RC46 (1)
A0A087WVZ5 (1)
A0A087WXI0 (1)
A0A087X1S3 (1)
A0A0A0MR66 (1)
A0A0A0MS51 (1)
A0A0A0MSA7 (1)
A0A0C4DG89 (1)
A0AVT1 (1)
A0FGR8 (1)
A0FGR8-2 (1)
A0FGR8-6 (1)
A0MZ66 (1)
A1L0T0 (1)
A1X283 (1)
A2BFH1 (1)
A2RRD8 (1)
A4D110 (1)
A4D1E9 (1)
A5A3E0 (1)
A5YKK6 (1)
A6NE02 (1)
A6NHL2 (1)
A6NHQ2 (1)
A6NHR9 (1)
A6NHT5 (1)
A6NIH7 (1)

ENSEMBL ID

ENSG00000170477 (1)
ENSG00000247315 (1)

CHEBI ID

CHEBI:21557 (3)
CHEBI:17385 (3)
CHEBI:16704 (3)
CHEBI:15891 (3)
CHEBI:16668 (3)
CHEBI:16737 (3)
CHEBI:16628 (2)
CHEBI:89461 (2)
CHEBI:17768 (2)
CHEBI:58148 (2)
CHEBI:60175 (2)
CHEBI:70959 (2)
CHEBI:24149 (2)
CHEBI:48430 (2)
CHEBI:50129 (2)
CHEBI:26271 (2)
CHEBI:49033 (2)
CHEBI:16344 (2)
CHEBI:184023 (2)
CHEBI:18186 (2)
CHEBI:16811 (2)
CHEBI:28300 (2)
CHEBI:43580 (2)
CHEBI:17140 (2)
CHEBI:16708 (2)
CHEBI:15728 (2)
CHEBI:16530 (2)
CHEBI:30838 (2)
CHEBI:48928 (2)
CHEBI:28044 (2)

Metabolite Name

Inosine (3)
3-hydroxykynurenine (2)
N-formylmethionine (2)
2'-deoxycytidine (2)
1-methylhistidine (2)
O-Tyrosine (2)
Cytidine (2)
5-hydroxyindoleacetate (2)
Pyridoxine (2)
Glutathione (2)
Cytosine (2)
Uridine (2)
Creatinine (2)
Hypoxanthine (2)
Hydroxyphenylglycine (1)
Phenyl Acetate (1)
Acetyl-methionine (1)
Melanin (1)
Indole-3-Acetaldehyde (1)
Zotepine (1)
Tyr-Thr-Arg (1)
Thr-His-Lys (1)
Tetrahydro-l-biopterin (1)
Terracinolide j (1)
Sulfadoxin (1)
Solstitialin a (1)
Sialyl lewis a (1)
Secbumeton (1)
Ronidazole (1)
(r)-lisofylline (1)

First Public Date

2025 (54)
2014 (49)
2024 (38)
2026 (34)
2022 (32)
2021 (29)
2023 (25)
2019 (25)
2020 (23)
2017 (21)
2018 (18)
2015 (12)
2016 (6)
2013 (5)
2012 (1)

Modification

4x(2)H labeled dimethylated residue (1)

Study type

Transcription profiling by array (737)
RNA-seq of coding RNA (122)
ChIP-seq (67)
Comparative genomic hybridization by array (57)
Methylation profiling by array (55)
Genotyping by array (21)
Other (15)
RNA-seq of coding RNA from single cells (15)
Transcription profiling by RT-PCR (11)
ChIP-chip by tiling array (10)
Cell line - High-throughput sequencing (9)
DNA-seq (8)
MicroRNA profiling by array (7)
RNA-seq of total RNA (6)
RNA-seq of non coding RNA (6)
Unknown experiment type (5)
Animal - High-throughput sequencing (5)
Human - High-throughput sequencing (4)
Cell line - One-color microarray (4)
Methylation profiling by high throughput sequencing (4)
Transcription profiling by SAGE (2)
Cell line - Single-cell sequencing (2)
Cell line - Methylation microarray (2)
MicroRNA profiling by high-throughput sequencing (2)
Human - Methylation microarray (2)
RNAi profiling by array (2)
ChIP-chip by array (2)
MicroRNA profiling by high throughput sequencing (2)
ATAC-seq (2)
ChIP-chip by SNP array (1)

Release Date

2013 (214)
2016 (202)
2015 (201)
2022 (176)
2014 (175)
2020 (170)
2021 (160)
2011 (154)
2012 (148)
2019 (142)
2017 (142)
2010 (134)
2018 (131)
2023 (124)
2024 (118)
2025 (103)
2008 (64)
2009 (60)
2026 (30)
2007 (15)
2006 (9)
2005 (3)

Lab affiliation

Edinburgh Cancer Research, CRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK (3)
UHN (3)
Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt am Main, Germany Frankfurt Cancer Institute, Frankfurt am Main, Germany Cardio-Pulmonary Institute, Frankfurt am Main, Germany (2)
School of Life Sciences, Tsinghua University, China (2)
1. Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA 2. UPMC Hillman Cancer Center, Pittsburgh, PA, USA 3. Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA 4. Department of Neurology, University of North Carolina, Chapel Hill, NC, USA (1)
1. Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA 2. UPMC Hillman Cancer Center, Pittsburgh, PA, USA 3. Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA 4. Department of Neurology, University of North Carolina, Chapel Hill, NC, USA (lab head) (1)
Analytical Chemistry Lab Fondazione Istituto Italiano di Tecnologia Via Morego 30, 16163 Genova Italy (1)
BCI Mass spectrometry Facility 1.02 & 1.03 1st floor Barts Cancer Institute Queen Mary, University of London John Vane Science Centre, Charterhouse Square, London EC1M 6BQ (1)
CIC bioGUNE Proteomics Platform Bizkaia Tech. Park Build 800 Derio 48160 Spain (1)
Centre for Regenerative Medicine, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh EH16 4UU, United Kingdom. Cancer Research UK Edinburgh Centre, University of Edinburgh, Edinburgh EH4 2XR, United Kingdom. (1)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States (1)
Department of Biotechnology, College of Life Science and Biotechnology, Korea University, Seoul, Republic of Korea (1)
Department of Genome Sciences, University of Washington, Seattle, USA (1)
Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India (1)
Department of Molecular Medicine, Cornell University, Ithaca, NY 14853 Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853 (1)
Department of Neurosurgery, Chongqing Research Center for Glioma Precision Medicine, Chongqing General Hospital, Chongqing University (1)
Department of Pharmacology and Toxicology (1)
Dept. of Pharmacology and Toxicology Univ. of TX Medical Branch Galveston, TX 77555 (1)
INSERM U1035 – BMGIC, Univ Bordeaux, 146 rue Leo Saignat, F-33000 Bordeaux, France. (1)
Institute of Functional Genomics, Univ. Montpellier, CNRS, INSERM, Montpellier, France (1)
Instituto de Neurociencias de Castilla y León (INCYL), Departamento de Bioquímica y Biología Molecular, Universidad de Salamanca, Spain (1)
Keck MS & Proteomics Resource Yale School of Medicine (1)
Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA (1)
Northwestern University (1)
Professor, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark (1)
Protein Analysis Core Facility German Cancer Research Center (DKFZ) (1)
Protemics Service CIC bioGUNE Bizkaia Tech. Park Build. 800 48160 Derio (Spain) (1)
Proteomics Platform CIC bioGUNE Bizkaia Tech. Park Build. 800 48160 Derio (Spain) (1)
Proteomics Platform CIDC bioGUNE Bizkaia Tech. Park Build. 800 48160 Derio 48160 Spain (1)
Proteomics Service CIC bioGUNE Bizkaia Tech. Park Build. 800 Derio 48160 Spain (1)

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Mitochondrial Transplantation of Brown Adipocytes Interferes with the Metabolism of Tumor Stem Cells and Inhibits the Recurrence of Brain Glioma after Operation

Glioblastoma multiforme (GBM) is highly aggressive, with treatment resistance and recurrence driven by metabolically plastic glioma stem cells (GSCs). Inspired by brown adipose tissue (BAT) thermogenesis, researchers transplanted BAT-derived mitochondria (BA-Mito) into GSCs, reducing stemness mar...

2025-08-27 | MTBLS12901 | MetaboLights

Aberrant L-Fucose accumulation and increased core fucosylation are metabolic liabilities in mesenchymal glioblastoma (Stem cell and cell line assays)

Glioblastoma (GBM) is a common and deadly form of brain tumor in adults. Dysregulated metabolism in GBM offers an opportunity to deploy metabolic interventions as precise therapeutic strategies. To identify the molecular drivers and the modalities by which different molecular subgroups of GBM exp...

2022-11-08 | MTBLS4708 | MetaboLights

Transcription profling of glioblastoma stem-like (GS) cell lines, conventional glioma cell lines and primary tumors

We compared a large panel of human glioblastoma stem-like (GS) cell lines, corresponding primary tumors and conventional glioma cell lines to identify cell lines that preserve the transcriptome of human glioblastomas most closely, thereby allowing identification of shared therapeutic targets. We us...

ORGANISM(S): Homo sapiens

2011-02-12 | E-GEOD-23806 | biostudies-arrayexpress

miRNA profiles of brain glioma stem cells and normal neural stem cells

A human microarray comprising 1658 human genome probes was used to evaluate the specific expression of miRNA between brian glioma stem cells (GSC) and normal neural stem cells(NSC). 2 total RNA samples are analyzed, brian glioma stem cells (GSC) and normal neural stem cells(NSC). cell type: brain g...

ORGANISM(S): Homo sapiens

2014-07-30 | E-GEOD-41032 | biostudies-arrayexpress

Transcriptome profiles of brain glioma stem cells and normal neural stem cells

A human cDNA microarray comprising 29,187 human genome probes was used to evaluate the transcriptional changes between brian glioma stem cells (GSC) and normal neural stem cells(NSC). There were 6 samples that were analyzed, 3 samples were from glioma stem cells and the other 3 samples form normal n...

ORGANISM(S): Homo sapiens

2014-07-30 | E-GEOD-41031 | biostudies-arrayexpress

Expression data from human glioma cancer stem cell (CSC) specimens following knockdown of GREM1

CSCs differentially secrete the BMP antagonist Gremlin1 compared to non-stem glioma populations. Knockdown of Gremlin1 decreases CSC proliferation and tumorigenicity, establishing Gremlin1 as an essential effector for CSC maintenance. We used a microarray to determine the gene expression programs t...

ORGANISM(S): Homo sapiens

2014-06-03 | E-GEOD-52846 | biostudies-arrayexpress

Functional analysis of HOXD9 in human gliomas and glioma cancer stem cells

HOX genes encode a family of homeodomain-containing transcription factors involved in the determination of cell fate and identity during embryonic development. They also behave as oncogenes in some malignancies. In this study, we found high expression of the HOXD9 gene transcript in glioma cell line...

ORGANISM(S): Homo sapiens

2011-04-16 | E-GEOD-28618 | biostudies-arrayexpress

Development of microRNA (miRNA) expression signatures for mouse glioma-initiating cells (GICs)

To identify a novel miRNA that is aberrantly expressed in GICs, we analyzed differences in miRNA expression between the mouse GICs, NSCL61 and OPCL61, showing characteristic features of cancer stem cell, and their parental cells by miRNA microarrays. neural stem cells, glioma-initiating cells (GICs)...

ORGANISM(S): Mus musculus

2015-04-07 | E-GEOD-61080 | biostudies-arrayexpress

Development of gene expression signatures for miR-340 overexpressing human glioma-initiating cells (GICs)

To identify functional targets of miR-340, we compared the gene expression profiles of miR-340 overexpressing human GICs with the profiles of their parental cells. The precursor form of miR-340 or control miRNA was overexpressed in glioma cells using miRNA lentiviral particles. The cells were incuba...

ORGANISM(S): Homo sapiens

2015-04-07 | E-GEOD-61078 | biostudies-arrayexpress

Development of microRNA (miRNA) expression signatures for human glioma-initiating cells (GICs)

To identify a novel miRNA that is aberrantly expressed in GICs, we analyzed differences in miRNA expression between the human GICs and glioma cell lines and neural stem cells by miRNA microarrays. We examined the miRNA expression profiles of five human GICs that were obtained from human glioma sampl...

ORGANISM(S): Homo sapiens

2015-04-07 | E-GEOD-61079 | biostudies-arrayexpress

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