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TranscriptomicsPyrococcus furiosus crRNAs associated with Cmr, Csa and Cst CRISPR-Cas systems
CRISPR-Cas immune systems function to defend prokaryotes against potentially harmful mobile genetic elements including viruses and plasmids. The multiple CRISPR-Cas systems (Types I, II, III) each recognize and target destruction of foreign invader nucleic acids via structurally and functionally div...
ORGANISM(S): Pyrococcus furiosus 
2015-07-10 | E-GEOD-65781 | biostudies-arrayexpress
TranscriptomicsPyrococcus furiosus crRNAs associated with the Cas RAMP module complex
Analysis of CRISPR RNAs from both total Pyrococcus furiosus RNA and those that co-purify with the Cmr complex, which has been predicted to be involved in RNA-mediated targeting of foreign RNAs in prokaryotes. Small RNAs (20 - 70 nts) were isolated either from total Pyrococcus furiosus RNA or RNAs i...
ORGANISM(S): Pyrococcus furiosus 
2012-01-31 | E-GEOD-33256 | biostudies-arrayexpress
UnknownEnhanced oxidative phosphorylation, re-organized intracellular signaling, and epigenetic de-silencing as revealed by oligodendrocyte translatome analysis after contusive spinal cord injury.
Not available
S-EPMC10692148 | biostudies-literature
UnknownEnhanced oxidative phosphorylation, re-organized intracellular signaling, and epigenetic de-silencing as revealed by oligodendrocyte translatome analysis after contusive spinal cord injury.
Not available
S-EPMC10402259 | biostudies-literature
TranscriptomicsTranscriptome and translational signaling following endurance exercise in trained skeletal muscle: impact of dietary protein
Impact of protein ingestion following 1 h intense cycling on the induced transcriptome and signaling in biopsy samples from endurance-trained men, relative to isocaloric control Single blind, randomized, crossover design comprising two experimental blocks. During the blocks, exercise and diet were c...
ORGANISM(S): Homo sapiens 
2011-11-21 | E-GEOD-27285 | biostudies-arrayexpress
TranscriptomicsLimb immobilization induces a coordinate down-regulation of mitochondrial and other metabolic pathways in men and women
Advancements in animal models and cell culture techniques have been invaluable in the elucidation of molecular events and mechanisms regulating muscle atrophy. However, few studies have examined muscle atrophy in humans using modern experimental techniques. The purpose of this study was to examine a...
ORGANISM(S): Homo sapiens 
2009-02-21 | E-GEOD-14901 | biostudies-arrayexpress
TranscriptomicsRNAseq profiling of a lpp0148 mutant compared to its isogenic parent Legionella pneumophila strain Paris
Comparaison of the transcriptional profile of mutant of the lpp0148 gene and the parent strain Legionella pneumophila strain Paris. lpp0148 codes for a protein with a ProQ domain (PFAM PF04352). A mutant of this gene was obtained by inserting a premature stop codon in the lpp0148 ORF. The lpp0148 mu...
ORGANISM(S): Legionella pneumophila 
2016-05-24 | E-MTAB-4094 | biostudies-arrayexpress
TranscriptomicsRNAseq profiling of a lpp1663 mutant compared to its isogenic parent Legionella pneumophila strain Paris
Comparaison of the transcriptional profile of mutant of the lpp1663 gene and the parent strain Legionella pneumophila strain Paris. lpp1663 codes for a protein with a ProQ domain (PFAM PF04352). A mutant of this gene was obtained by deleting the lpp1663 ORF and replacing it with a gene confering res...
ORGANISM(S): Legionella pneumophila 
2020-09-01 | E-MTAB-4095 | biostudies-arrayexpress
GenomicsMutational evolution in a lobular breast tumour profiled at single nucleotide resolution
We have used next generation sequencing to sequence genomes (>43-fold coverage) and transcriptomes of an oestrogen-receptor-alpha-positive metastatic lobular breast cancer at depth. We found 32 somatic non-synonymous coding mutations present in the metastasis, and measured the frequency of these som...
EGAS00000000054 | EGA
GenomicsEGAD00000000047
Signal data for from 3 recurrent and 1 ovarian primary Granulosa Cell Tumour samples
EGAD00000000047 | EGA
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