Glp1r - OmicsDI

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Single-nucleus RNA-seq of FACS-enriched Glp1r-Sun1-sfGFP nuclei from mouse hypothalamus, dorsal vagal complex, and nodose ganglion

Glucagon-like peptide-1 receptor (GLP1R) agonists such as semaglutide reduce food intake and body weight, and Glp1r-expressing neurons in the hypothalamus and hindbrain mediate these effects. To profile these cells directly, Glp1r-Cre mice were crossed to the Gt(ROSA)26Sor-CAG-Sun1-sfGFP reporter, w...

ORGANISM(S): Mus musculus

2026-09-14 | E-MTAB-17566 | biostudies-arrayexpress

Transcriptome sequencing of PDLSCs induced by GIPR and GLP1R alteration

Our previous study (Environ Pollut. 2023;323:121307) has indicated that Glucose-dependent insulinotropic polypeptide receptor (GIPR) and Glucagon-like peptide-1 receptor (GLP1R) are down-regulated in periodontal ligament stem cells (PDLSCs) by cigarette and E-cig. In the current study, we focus on i...

ORGANISM(S): Homo sapiens

2025-07-25 | E-MTAB-15372 | biostudies-arrayexpress

Transcriptome sequencing of PDLSCs induced by GIPR and GLP1R alteration

PRJEB93789 | ENA

Transcriptomics of Glp1r-expressing cells in mouse hypothalamus tissue

PRJNA818970 | ENA

Human GLP1R variants affecting GLP1R cell surface expression are associated with impaired glucose control and increased adiposity.

Not available

S-EPMC11610247 | biostudies-literature

Reagents and models for detecting endogenous GLP1R and GIPR.

Not available

S-EPMC8669301 | biostudies-literature