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ProteomicsRyR2-mediated calcium leak increases glyoxalase I in the aging brain
Ryanodine receptor 2 (RyR2) mediated chronic calcium leak in the brain has been implicated in patients with late-onset Alzheimer’s disease (LOAD) and from aging macaques, but the direct downstream consequences of calcium leak remain unclear. Here, we present that RyR2 mediated chronic calcium leak l...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-25 | PXD053288 | Pride
Glyoxalase i  ryanodine receptor 2  calcium dysregulation  aging  macaque  prefrontal cortex  hippocampus  proteomics 
ProteomicsAluminum and salt induced protein changes in tomato overexpressing a glyoxalase I gene
In this project, seedlings of tomato (Solanum lycopersicum) ‘Money Maker’ plants overexpressing a glyoxalase I gene were treated under 20 µM Al3+ and salt (200 mM NaCl) for two weeks. The treatments were conducted in hydroponic solutions in a greenhouse at 24±2C without supplemental light. Roots ha...
ORGANISM(S): Solanum lycopersicum 
2020-04-09 | PXD009456 | Pride
Aluminum Root Methylglyoxal Salt 
UnknownTrypanothione-dependent glyoxalase I in Trypanosoma cruzi.
Not available
S-EPMC1652828 | biostudies-literature
UnknownA trypanothione-dependent glyoxalase I with a prokaryotic ancestry in Leishmania major.
Not available
S-EPMC516525 | biostudies-literature
UnknownStructural variation in bacterial glyoxalase I enzymes: investigation of the metalloenzyme glyoxalase I from Clostridium acetobutylicum.
Not available
S-EPMC3207458 | biostudies-literature
UnknownGlyoxalase I activity affects Arabidopsis sensitivity to ammonium nutrition.
Not available
S-EPMC9700585 | biostudies-literature
UnknownStructure of the novel monomeric glyoxalase I from Zea mays.
Not available
S-EPMC4601366 | biostudies-literature
UnknownSalt-Tolerant Phenomena, Sequencing and Characterization of a GlyoxalaseI (Jojo-Gly I) Gene from Jojoba in Comparison with Other Glyoxalase I Genes.
Not available
S-EPMC7601343 | biostudies-literature
UnknownNovel glyoxalase-I inhibitors possessing a "zinc-binding feature" as potential anticancer agents.
Not available
S-EPMC4993257 | biostudies-literature
Unknown<i>sll1019</i> and <i>slr1259</i> encoding glyoxalase II improve tolerance of <i>Synechocystis</i> sp. PCC 6803 to methylglyoxal- and ethanol- induced oxidative stress by glyoxalase pathway.
Not available
S-EPMC11577758 | biostudies-literature
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