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As we have found that H3K56cr can crosslink with GLYR1 in living cells, we now perform H3K*cr Site-Link in GLYR1 overexpressed cells. The subsequent 365-nm light irradiation could activate the diazirine and covalently capture potential effector proteins on native chromatin in living cells. The cross...
ORGANISM(S): Homo sapiens (Human) 
2023-03-06 | PXD033960 | Pride
We performed transcriptome sequencing on GLYR1-positive and GLYR1-negative human pancreatic ductal adenocarcinoma (PDAC) to shed light on the transcriptional changes of GLYR1-positive PDAC.
ORGANISM(S): Homo sapiens 
2023-01-01 | GSE196590 | GEO
Transcriptome Sequencing of GLYR1-positive human pancreatic ductal adenocarcinoma.
NDF/GLYR1 Promotes RNA Polymerase II Processivity via Pol II Binding and Nucleosome Destabilization
H3K36me3 Reader NPAC/GLYR1 Recruits H3K4 Demethylase LSD2/KDM1B to Modulate Active Gene Transcription
NDF/GLYR1 Promotes RNA Polymerase II Processivity via Pol II Binding and Nucleosome Destabilization
Congenital Heart Disease (CHD) is present in 1% of live births, and while large-scale genetic studies have uncovered genes associated with CHDs, identifying causal mutations remains a challenge. We hypothesized that genetic determinants for CHDs could be found in the protein interactomes of GATA4 an...
ORGANISM(S): Homo sapiens 
2022-02-18 | GSE159411 | GEO
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