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ProteomicsHost cholesterol modulates the generation and enrichment of persister population during Mycobacterium tuberculosis infection.
Post-translational modifications (PTMs) confer diversity to regulatory mechanisms that control various cellular pathways. Two of the most extensively studied PTMs are phosphorylation and acetylation. Together, they are known to regulate the stability and activity of proteins in both eukaryotes and p...
ORGANISM(S): Mycobacterium tuberculosis M24 
2020-10-16 | PXD022028 | Pride
Proteomics Lc-ms/ms 
ProteomicsA conserved aminopeptidase PepN, exhibits divergent traits in pathogenic and non- pathogenic mycobacteria
A conserved aminopeptidase PepN, exhibits divergent traits in pathogenic and non- pathogenic mycobacteria
ORGANISM(S): Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Mycobacterium tuberculosis H37Rv 
2019-11-12 | PXD008790 | Pride
Aminopeptidase pepn Mycobacteria Lc-ms/ms 
ProteomicsProteome analysis revealed the essential functions of protein phosphatase PP2A in the induction of Th9 cells
we performed proteome analysis of Th9 cells to understand the involvement of proteins that might be crucial for the anti-tumor functions of Th9 cells. Here we show for the first time a comprehensive proteomic analysis of murine Th0 and Th9 cells, which identified 1451 total proteins among which 1367...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD019506 | Pride
Proteomics Pp2a Mass spectrometry Th9 cells 
ProteomicsQuantitative phosphoproteome analyses of human macrophage-like THP-1 cells following infection with virulent Mycobacterium tuberculosis and avirulent M. bovis BCG, respectively.
In this project we conducted a comprehensive analysis of expression and global phosphorylation status of the host proteins following infection with virulent and avirulent mycobacteria. Our objective is to identify previously uncharacterized proteins of host macrophages that are specifically expresse...
ORGANISM(S): Homo sapiens (Human) 
2020-05-15 | PXD013171 | Pride
M. bovis bcg Mycobacterium tuberculosis Macrophages Proteome Phosphoproteome Mass-spectrometer 
TranscriptomicsTranscriptome profiling of reproductive stage flag leaves of wheat from drought susceptible parent WL711, drought tolerant parent C306 and drought susceptible and drought tolerant RIL bulks in irrigated and drought condition
The aim of the study was to identify candidate genes responsible for drought tolerance trait between a pair of wheat varieties ( WL711 and C306) and correspondng progeny bulks (10 drought susceptible RILs and 10 drought tolerant RILs) by combining QTLs analysis with expression analysis. Microarr...
ORGANISM(S): Triticum aestivum 
2012-04-29 | E-GEOD-30436 | biostudies-arrayexpress
ProteomicsTargeting CHAF1B enhances interferon activity in myeloproliferative neoplasms
Interferons (IFNs) are cytokines with potent anti-neoplastic properties and significant clinical activity in the treatment of myeloproliferative neoplasms (MPNs). The use of pegylated IFN for the treatment of MPNs has been of particular interest, with several clinical trials establishing clinical r...
ORGANISM(S): Homo sapiens (Human) 
2023-05-15 | PXD037376 | Pride
Chaf1b Myeloproliferative neoplasms Interferon 
UnknownDominant variants in major spliceosome U4 and U5 small nuclear RNA genes cause neurodevelopmental disorders through splicing disruption.
Not available
S-EPMC12165858 | biostudies-literature
ProteomicsComprehensive_map_HsUrine
A comprehensive map of the Human Urinary Proteome, non-glyco
ORGANISM(S): Homo Sapiens (human) 
2011-12-31 | PAe004096 | PeptideAtlas
ProteomicsHs_Eye_vitreous_humor
Hs_Eye_vitreous_humor SCX and off-gel
ORGANISM(S): Homo Sapiens (human) 
2014-12-31 | PAe003752 | PeptideAtlas
ProteomicsA proteomic map of the human aqueous humor
The aqueous humor is a colourless, transparent fluid that fills the anterior chamber of the eye. It has an important role to play in maintaining the intraocular pressure of the eye and providing nourishment to avascular structures such as the lens and cornea. It is also essential for providing a cle...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-29 | MSV000081764 | MassIVE
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