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Gold salts has been used in the treatment of rheumatoid arthritis but has been replaced by biologicals such as TNF-alpha inhibitors. The mechanisms behind the anti-inflammatory effect of metallic gold ions are still unknown, however, recent data showed that charged gold atoms are released from pure ...
ORGANISM(S): Homo sapiens 

While analytical techniques in natural products research massively shifted to liquid chromatography-mass spectrometry, lichen chemistry remains reliant on limited analytical methods, Thin Layer Chromatography being the gold standard. To meet the modern standards of metabolomics within lichenochem...

2019-07-22 | MTBLS999 | MetaboLights
Triticeae crops are major contributors to global food production and ensuring their capacity to reproduce and generate seeds is critical. However, despite their importance our knowledge of the proteins underlying Triticeae reproduction is severely lacking and this is not only true of pollen and sti...
ORGANISM(S): x Triticosecale 
2023-03-08 | PXD038905 | Pride
Lowered activity of the insulin/IGF signaling (IIS) network can ameliorate the effects of ageing in model organisms and, possibly, humans. Remodelling of the RNA transcriptome of long-lived IIS mutants has been extensively documented, but is only weakly predictive of consequent changes in protein ex...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2017-09-13 | PXD006225 | Pride
Successful pollination brings together the mature pollen grain and stigma papilla to initiate an intricate series of molecular processes meant to eventually enable sperm cell delivery for fertilization and reproduction. At maturity, the pollen and stigma cells have acquired proteomes comprising the...
ORGANISM(S): Brassica carinata 
2021-03-13 | PXD017953 | Pride
We investigated tissue-specific regulation of gene expression in a long lived Drosophila IIS mutant (dilp2-3,5) compared to its control (wDah). As in the majority of Drosophila laboratory strains, the endosymbiont Wolbachia was present; in the absence of Wolbachia, life extension through dilp2-3,5 i...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2021-04-21 | PXD011589 | Pride
Investigation of whole genome expression pattern of 24 and 48 hours post fertilization Danio Rerio embryos exposed to 1.5nm MES- and TMAT- AuNPs. TMAT is a positively charged (cationic) ligand, and MES is a negatively charged (anionic) ligand. Embryos were exposed to 10ug/mL of 1.5nm TMAT-AuNPs, 50u...
ORGANISM(S): Danio rerio 
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