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TranscriptomicsHepatocellular carcinomas (HCC) in mice transduced in utero with feline immunodeficiency virus-based vectors (CGH)
Fetal mice (16 days gestation) were administered FIV-based lentiviral viral particles containing the gene encoding EGFP. Six liver tumors developed in three mice (1 male, 2 females) between the ages of 273 and 484 days, each mouse developed 2 tumors. These tumors and non-tumorous liver tissue from ...
ORGANISM(S): Mus musculus 
2013-09-11 | E-GEOD-25900 | biostudies-arrayexpress
TranscriptomicsHepatocellular carcinomas (HCC) in mice transduced in utero with feline immunodeficiency virus-based vectors (expression)
Fetal mice (16 days gestation) were administered feline immunodeficiency virus (FIV)-based lentiviral viral particles containing the gene encoding GFP. Six liver tumors developed in three mice between the ages of 273 and 484 days, each mouse developed 2 tumors. These tumors and non-tumorous liver t...
ORGANISM(S): Mus musculus 
2013-09-11 | E-GEOD-19306 | biostudies-arrayexpress
TranscriptomicsChronic liver inflammation-induced double strand DNA breaks enhance hepatocarcinogenesis
Surgical resection is the preferred treatment for Hepatocellular carcinoma; however, it induces tumor recurrence. Our objective was to understand the molecular mechanisms linking liver regeneration under chronic-inflammation to tumorigenesis. Mdr2-knockout mice, a model of inflammation-associated ca...
ORGANISM(S): Mus musculus 
2010-01-03 | E-GEOD-14539 | biostudies-arrayexpress
UnknownGut microbial signature in lung cancer patients highlights specific taxa as predictors for durable clinical benefit.
Not available
S-EPMC9898251 | biostudies-literature
TranscriptomicsTranscription profiling of MDR2 knockout mice vs heterozygotes sampled at multiple time points in the early stages of liver carcinogenesis to identify the molecular mechanisms of HCC initiation and promotion
We studied the molecular mechanisms of hepatocellular carcinoma (HCC) initiation and promotion using the Mdr2-knockout (Mdr2-KO) mice at pre-cancerous stages of liver disease. These mice lack the liver-specific P-glycoprotein responsible for phosphatidylcholine transport across the canalicular membr...
ORGANISM(S): Mus musculus 
2007-11-23 | E-GEOD-4612 | biostudies-arrayexpress
UnknownMacular Morphology and Visual Acuity in the Second Year of the Comparison of Age-Related Macular Degeneration Treatments Trials.
Not available
S-EPMC4998967 | biostudies-literature
UnknownPredominantly Persistent Intraretinal Fluid in the Comparison of Age-related Macular Degeneration Treatments Trials.
Not available
S-EPMC10282893 | biostudies-literature
UnknownThiazolidinedione use and retinal fluid in the comparison of age-related macular degeneration treatments trials.
Not available
S-EPMC10245276 | biostudies-literature
UnknownBaseline predictors for one-year visual outcomes with ranibizumab or bevacizumab for neovascular age-related macular degeneration.
Not available
S-EPMC3536921 | biostudies-literature
UnknownSubretinal Hyperreflective Material in the Comparison of Age-Related Macular Degeneration Treatments Trials.
Not available
S-EPMC4549177 | biostudies-literature
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