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UnknownProtection against SARS-CoV-2 Omicron BA.1 variant challenge in macaques by prime-boost vaccination with Ad26.COV2.S and SpFN.
Not available
S-EPMC9683731 | biostudies-literature
ProteomicsCentral nervous system involvement of acute lymphoblastic leukemia depends on mRNA translation and complement component 3
Central nervous system (CNS) dissemination of B-precursor acute lymphoblastic leukemia (B-ALL) has a poor prognosis and remains a therapeutic challenge with few recent advances in therapy. Leptomeningeal disease is particularly common in the high risk subgroup of KMT2A-rearranged B-ALL (KMT2A-r B-AL...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD022411 | Pride
Lc-ms Leukemia Lfq 
TranscriptomicsTranscription profiling of human AML cell line OCI/AML2 treated with valproic acis and all trans retinoic acid
Purpose: Treatment of acute promyelocytic leukemia (APL) with the retinoid, all trans retinoic acid (ATRA), along with standard chemotherapy has significantly improved survival compared to chemotherapy alone1. ATRA mediates its benefit in APL by overcoming the transcriptional block mediated by PML-R...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-2668 | biostudies-arrayexpress
TranscriptomicsWhole-genome methylation analysis (450k) of school aged children prenatally exposed to alcohol vs controls
We tested a hypothesis that prenatal alcohol exposure may lead to epigenetic alterations to the DNA resulting in attentional and cognitive alterations of the children. 6-9 year old children school children of the Franconian Cognition and Emotion Studies (FRANCES) cohort which were tested for an obj...
ORGANISM(S): Homo sapiens 
2018-05-12 | E-MTAB-6730 | biostudies-arrayexpress
UnknownWhole Genome Sequencing Assessing Impact of Diabetes Mellitus on Tuberculosis Mutations and Type of Recurrence in India.
Not available
S-EPMC9477453 | biostudies-literature
UnknownFood insecurity and neurocognitive function among women living with or at risk for HIV in the United States.
Not available
S-EPMC7657325 | biostudies-literature
UnknownMetabolic Changes Associated With the Use of Integrase Strand Transfer Inhibitors Among Virally Controlled Women.
Not available
S-EPMC7577246 | biostudies-literature
UnknownPatterns and Trajectories of Anal Intercourse Practice Over the Life Course Among US Women at Risk of HIV.
Not available
S-EPMC9559060 | biostudies-literature
UnknownAutomated coronary calcium scoring using deep learning with multicenter external validation.
Not available
S-EPMC8169744 | biostudies-literature
ProteomicsThe CDK12-inhibitor CR8 mediates Cyclin K degradation through the CUL4-RBX1-DDB1 E3 ubiquitin ligase
Small molecules have been identified that induce protein-protein interactions between a substrate and a ubiquitin ligase, resulting in targeted protein degradation. Such molecular glue compounds, unlike traditional enzyme inhibitors, act sub-stoichiometrically to catalyse rapid depletion of previous...
ORGANISM(S): Homo sapiens (Human) 
2020-06-10 | PXD016188 | Pride
Cr8 Cyclin k Molecular glue Cdk12 Ubiquitin Crl4ddb1 
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