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ProteomicsProteomic changes in mouse brain expressing WT and mutant (S3) alleles of the prion protein
Label-free quantification of proteomic changes in mouse expressing WT, mutant (S3) prion protein, and PrP-KO mouse. Three biological replicates were included per condition. In-gel digestion of the proteins extracted from brain generated 6 fractions per replicate.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-07-27 | MSV000092545 | MassIVE
ProteomicsN-terminal acetylation for identification of cleavage sites on immunoprecipitated PrP
In-gel N-terminal acetylation of immunoprecipitated prion protein for identification of cleavage sites. Mouse expressing either WT or mutant (S3) form of PrP were used in this study. Three replicates from single brains were included in this experiment.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-07-27 | MSV000092543 | MassIVE
ProteomicsSubtiligase N-terminomics for identification of cleavage sites in mice brain and immunoprecipitated PrP
Subtiligase-based N-terminomics (Abu N-terminal tagging) of whole mouse brain and immunoprecipitated prion protein. Mouse expressing either WT or mutant (S3) form of PrP were used in this study. Five replicates for single brain experiments and one replicate for combined brains approach are included....
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-07-27 | MSV000092542 | MassIVE
ProteomicsIdentification of proteolytic events during C2C12 myoblast differentiation
Identification of product of proteolysis during C2C12 myoblast differentiation using subtiligase N-terminomics. Different cell populations collected during a time-course of differentiation (4 days) were used for N-terminal labeling in a forward degradomics approach (n=2). Day0 population= Myoblasts,...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2024-05-01 | MSV000094657 | MassIVE
ProteomicsLabel-free quantification of proteomic changes during C2C12 myoblast differentiation
Global proteome comparison between five cell populations isolated during a 4-day differentiation process in C2C12 myoblasts. A total of 5 replicates were in-column digested and data was collected in data independent acquisition mode on a Lumos Tribrid instrument for label free-quantification of prot...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2024-05-01 | MSV000094656 | MassIVE
ProteomicsSARS-CoV-2 Mpro subtiligase-mediated N-terminomics in Jurkat
Subtiligase-based N-terminomics study with 0.5 uM SARS-CoV-2 Mpro in Jurkat cell lysates. Independent duplicates were injected with (L20200924-06, L20200924-07) and without FAIMS (L20200927-01-001, L20200927-02-002).
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-12-17 | MSV000088584 | MassIVE
ProteomicsSARS-CoV-2 Mpro subtiligase-mediated N-terminomics in A549
Subtiligase-based N-terminomics study with 0.5 uM of recombinant SARS-CoV-2 Mpro in A549 cell lysates, in duplicate experiments.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-12-17 | MSV000088583 | MassIVE
ProteomicsReverse N-terminomics of SARS-CoV-2 PLpro in A549
Subtiligase based N-terminomics (Abu N-terminal tagging) of two A549 cell lysate replicates incubated with SARS-CoV-2 PLpro.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-08-12 | MSV000090125 | MassIVE
ProteomicsReverse N-terminomics of SARS-CoV-2 PLpro in Jurkat
Subtiligase based reverse N-terminomics (Abu N-terminal tagging) of two Jurkat cell lysate replicates incubated with SARS-CoV-2 PLpro.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-08-12 | MSV000090124 | MassIVE
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