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MetabolomicsUntargeted LC-MS metabolomics of redclaw crayfish gonads
Untargeted LC-MS metabolomics was performed on 20 Cherax quadricarinatus gonad samples in four groups n=5 each plus three pooled QC samples. Positive- and negative-ion mzXML files were generated using a Thermo Scientific Orbitrap Exploris 120. The submitted files contain centroided full-scan MS1 dat...
2026-09-04 | MTBLS15185 | MetaboLights
TranscriptomicsTranscription profiling of XX and XY sorted mouse somatic support cells and XX and XY mouse whole gonads to identify potential new mammalian gonadal sex determining genes.
Gonadal sex determining (GSD) genes that initiate fetal ovarian and testicular development and differentiation are expressed in the cells of the urogenital ridge that differentiate as somatic support cells (SSCs), i.e., granulosa cells of the ovary and Sertoli cells of the testis. To identify potent...
ORGANISM(S): Mus musculus 
2007-11-30 | E-GEOD-4928 | biostudies-arrayexpress
TranscriptomicsmiRNA profiling in male and female chicken embryonic gonads during sexual differentiation
MicroRNAs (miRNAs) are a highly conserved class of small RNAs which function in a sequence-specific manner to post-transcriptionally regulate expression of target genes. Tissue-specific miRNA expression studies have discovered numerous functions for miRNAs in various aspects of embryonic developmen...
ORGANISM(S): Gallus gallus 
2010-05-18 | E-GEOD-13154 | biostudies-arrayexpress
TranscriptomicsExpression analysis of Wv/Wv fetal gonads
Following sex determination, XY and XX gonads develop into a testis and an ovary, respectively. Depending on the sex of the gonad, resident germ cells will subsequently be committed to either spermatogenesis or oogenesis. In this study we took advantage of the Wv/Wv mouse genetic model, in which gon...
ORGANISM(S): Mus musculus 
2010-12-20 | E-GEOD-23908 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of gonadal somatic cells from gonads of male and female transgenic pSF1-eGFP mice
Gene expression profiling of FACS sorted GFP+ve cells from sexed gonads of transgenic pSF1-eGFP mice
ORGANISM(S): Mus musculus 
2007-12-15 | E-GEOD-3463 | biostudies-arrayexpress
TranscriptomicsCharacterization of Sus scrofa small RNA sequences present in both female and male gonads
We used deep sequencing to characterize 3 families of sRNAs (piRNAs, miRNAs, and tRFs) present in Sus scrofa gonads and focused on the sRNA fraction present in both male and female gonads. Of the sequences detected in the testes, 2.6% of piRNAs, 9% of miRNAs, and 10% of tRFs were also present in the...
ORGANISM(S): Sus scrofa 
2014-07-27 | E-GEOD-57414 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of mouse embryo gonad during the critical period of sex determination
Expression profiling of micro RNAs in mouse embryonic gonads before (11.5 days post coitum) and after (13.5 days post coitum) the critical period of sex determination
ORGANISM(S): Mus musculus 
2012-05-11 | E-MEXP-2252 | biostudies-arrayexpress
ProteomicsRibosome heterogeneity in Drosophila melanogaster gonads through paralog-switching
Ribosomes have long been thought of as homogeneous macromolecular machines, but recent evidence suggests they are heterogeneous and could be specialised to regulate translation. Here, we have isolated ribosomal complexes and characterised their protein content across 4 tissues of Drosophila melanoga...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2021-07-22 | PXD026227 | Pride
Gonads Testis Tmt-ms Ribosome Paralog Drosophila melanogaster Ovary 
TranscriptomicsMytilus galloprovincialis: development of female gonads
Transcriptional profiling of the mantle tissue across the four stages of female gonads development (winter peak) in a natural population of the marine mussel Mytilus galloprovincialis sampled in the Bizerta Lagoon, Tunisia, across November 2007 -March 2008. Background: Seasonal environmental change...
ORGANISM(S): Mytilus galloprovincialis 
2011-06-06 | E-GEOD-23049 | biostudies-arrayexpress
Transcriptomicsgonads gene expression profiling in WT and Sox9flox/flox; Sf1:creTr/+ mice
In mammals, gonadal differentiation is the first step of sex determination, and the transcription factor Sox9 promotes testis differentiation. Here we used the XY Sox9flox/flox; Sf1:creTr/+ mouse model and show that the lack of Sox9 expression induces a full sex reversal of E13.5 XY Sox9flox/flox; S...
ORGANISM(S): Mus musculus 
2011-11-01 | E-GEOD-21650 | biostudies-arrayexpress
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