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A major impediment to the effective treatment of patients with PDAC (Pancreatic Ductal Adenocarcinoma) is the molecular heterogeneity of the disease, which is reflected in an equally diverse pattern of clinical responses to therapy. We developed an efficient strategy in which PDAC samples from 17 co...
ORGANISM(S): Homo sapiens 
Peptide vaccination remains a viable approach to induce T-cell mediated killing of tumours. To identify potential T-cell targets for Triple-Negative Breast Cancer (TNBC) vaccination, we examined the effect of the pro-inflammatory cytokine interferon-γ (IFNγ) on the transcriptome, proteome and immuno...
ORGANISM(S): Homo sapiens (Human) 
2021-05-13 | PXD023044 | Pride
Peptide vaccination remains a viable approach to induce T-cell mediated killing of tumours. To identify potential T-cell targets for Triple-Negative Breast Cancer (TNBC) vaccination, we examined the effect of the pro-inflammatory cytokine interferon-γ (IFNγ) on the transcriptome, proteome and immuno...
ORGANISM(S): Homo sapiens (Human) 
2021-05-13 | PXD023038 | Pride
Breast cancer includes a large number of genomic segments defined by targetable genomic alterations. This multicentre molecular screening program aims to identify these abnormalities in individual patients in order to propose a targeted therapy matched to the genomic alteration.
ORGANISM(S): Homo sapiens 
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