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UnknownHelicobacter pylori SlyD stabilizes TPT1 via hnRNPK and enhances OCT1-mediated CDX2 transcriptional activation to drive gastric intestinal metaplasia.
Not available
S-EPMC11803974 | biostudies-literature
UnknownHpSlyD inducing CDX2 and VIL1 expression mediated through TCTP protein may contribute to intestinal metaplasia in the stomach.
Not available
S-EPMC5442128 | biostudies-literature
UnknownMucin phenotype-based deep learning framework for intestinal metaplasia-carcinogenesis progression prediction.
Not available
S-EPMC12820390 | biostudies-literature
ProteomicsPUMILIO Proteins in Colorectal Cancer: Tumor Growth Promoting Function and Potential as Therapeutic Targets
We employ Mass spectrum to investigate proteome of Pum1-Knockout, Pum2-Knockout and WT conditions in human colorectal cancer cell line Hct116. Overall design: In order to investigate whether Pum1 and Pum2 regulate their targets at their protein levels, we used Pum1-Knockout, Pum2-Knockout and WT Hct...
ORGANISM(S): Homo Sapiens 
2021-07-23 | PXD027513 |
ProteomicsUrinary Proteomic Profiles of Anterior Cruciate Ligament Reconstruction Patients
A total of 30 ACLR patients, at least 9 months post-surgery, were recruited. Patients were divided into RTS and non-RTS groups based on their ability to return to sport, recovery to pre-injury Tegner levels, and a leg symmetry index of 85% on the single-leg hop test. Urine samples were analyzed usin...
ORGANISM(S): Homo Sapiens 
2025-02-19 | PXD060941 |
ProteomicsLoss of Drosophila nucleostemin 1 disrupts ribosomal protein homeostasis and rRNA processing to trigger apoptosis via the Xrp1/Irbp18 complex
In this study, we investigate the role of Ns1 in proliferating epithelial tissues using the Drosophila wing imaginal disc as a model. We demonstrate that knocking down Ns1 in wing discs leads to strong apoptosis. However, unlike the reported effect on overexpressed RPs, we did not observe nucleolar ...
ORGANISM(S): Drosophila Melanogaster 
2026-03-02 | PXD075076 |
ProteomicsComparative Analysis of Soybean Seed Proteome Based on Different Mass Spectrometry Acquisition Strategies
This study established a soybean seed proteome database and analyzed the raw mass spectrometry data of BoxCar and DIA on MaxQuant based on this database. Subsequently, the three mass spectrometry acquisition strategies, DDA, DIA and BoxCar, were compared for their depth of protein identification, da...
ORGANISM(S): Glycine Max 
PXD052278 |
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