Gonzalez M Isabel MI

Show results for

Unknown (14)
Metabolomics (2)
Proteomics (1)

Organisms

Mus musculus (1)

Repository

MetaboLights (2)
pride (1)

Tissue

B cell (1)
Spleen (1)

Technology Type

Mass spectrometry (2)
Affinity purification coupled with mass spectrometry proteomics (1)
Mass Spectrometry (1)

Instrument Platform

Direct infusion MS - Negative (1)
Direct infusion MS - Positive (1)
Liquid Chromatography MS - (1)

Publication Date

2023 (1)
2022 (1)
2018 (1)

CHEBI ID

CHEBI:16610 (2)
CHEBI:100241 (1)
CHEBI:10072 (1)
CHEBI:10219 (1)
CHEBI:10365 (1)
CHEBI:113 (1)
CHEBI:125201 (1)
CHEBI:131434 (1)
CHEBI:131700 (1)
CHEBI:132244 (1)
CHEBI:132612 (1)
CHEBI:133199 (1)
CHEBI:133343 (1)
CHEBI:133512 (1)
CHEBI:133565 (1)
CHEBI:133678 (1)
CHEBI:137725 (1)
CHEBI:138367 (1)
CHEBI:1387 (1)
CHEBI:141700 (1)
CHEBI:1427 (1)
CHEBI:143107 (1)
CHEBI:14314 (1)
CHEBI:14336 (1)
CHEBI:143794 (1)
CHEBI:144380 (1)
CHEBI:145221 (1)
CHEBI:145223 (1)
CHEBI:145239 (1)
CHEBI:15035 (1)

Metabolite Name

Spermidine (2)
1,7-dimethyluric acid (1,7-DMU) (1)
1-O-methylpyrogallol (1-MePYR) (1)
1-hydroxypyrene glucuronide (HPYR-G) (1)
1-methylhistamine (1)
1-methylhistidine (1)
1-methyluric acid (1-MU) (1)
1-methylxanthine (1-MX) (1)
11-deoxycortisol (1)
17-hydroxyprogesterone (1)
2,4,6-trihydroxybenzaldehyde (THBAld) (1)
2,4-dihydroxybenzoic acid (2,4-DHBA) (1)
2,4-dihydroxybenzophenone (BP1) (1)
2,5-dimethylfuran-3-one (2,5-DMF) (1)
2,5-furandicarboxylic acid (2,5-FDCA) (1)
2,6-diaminopimelic acid (1)
2,6-dihydroxybenzoic acid (2,6-DHBA) (1)
2-O-methylpyrogallol (2-MePYR) (1)
2-aminoadipic acid (1)
2-aminophenol (2-APh) (1)
2-furoylglycine (2-FG) (1)
2-hydroxy-4-methoxybenzophenone (BP3) (1)
2-hydroxybenzoic acid (2-HBA) (1)
2-hydroxyglutaric acid (1)
2-hydroxyhippuric acid (2-HHA) (1)
2-hydroxyphenylacetic acid (2-HPAA) (1)
2-isopropylmalic acid (1)
2-methylbutyrylglycine (2-MeC4-Gly) (1)
2-methylglutaric acid (MeC5-DC) (1)
2-oxoadipic acid (1)

Release Date

2022 (4)
2020 (3)
2024 (2)
2025 (1)
2021 (1)
2019 (1)
2018 (1)
2017 (1)

Lab affiliation

Pontificia Universidad Católica de Chile Department of Cellular and Molecular Biology Av. B. O’Higgins 340. Santiago, Chile Phone: 56-2-23541843 (1)

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Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models

Reversible and sub-lethal stresses to the mitochondria elicit a program of compensatory responses that ultimately improve mitochondrial function, a conserved anti-aging mechanism termed mitohormesis. Here, we show that harmol, a member of the beta-carbolines family with anti-depressant properties, i...

2023-05-26 | MTBLS7533 | MetaboLights

Characterization of the Human Exposome by a Comprehensive and Quantitative Large-Scale Multianalyte Metabolomics Platform

The exposome, defined as the cumulative measure of external exposures and associated biological responses throughout the lifespan, has emerged in recent years as a cornerstone in biomedical sciences. Metabolomics stands out here as one of the most powerful tools for investigating the interplay betwe...

2022-02-17 | MTBLS1906 | MetaboLights

Galectin-8 facilitates B cell responses to surface-tethered antigens by promoting antigen extraction at the B cell synapse

Complete activation of B cells relies on their capacity to extract surface-tethered 35 antigens at the immune synapse by either exerting mechanical forces or promoting 36 their proteolytic degradation through lysosome secretion. Whether antigen extraction 37 can be tuned by local cues originating...

ORGANISM(S): Mus musculus (Mouse)

2018-12-14 | PXD011522 | Pride