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ProteomicsEpigenetic inactivation of the autophagy-lysosomal system in the Parkinson’s disease appendix
The gastrointestinal tract may be a site of origin for α-synuclein (α-syn) pathology in idiopathic Parkinson’s disease (PD), and an abundance of aggregated α-syn has recently been demonstrated in both the healthy and PD appendix. However, the molecular changes that enable gut α-syn aggregates to con...
ORGANISM(S): Homo sapiens (Human) 
2021-07-06 | PXD021757 | Pride
Autophagy-lysosomal system Appendix Parkinson's disease 
ProteomicsEpigenetic inactivation of the autophagy-lysosomal system in the Parkinson’s disease appendix
The gastrointestinal tract may be a site of origin for α-synuclein (α-syn) pathology in idiopathic Parkinson’s disease (PD), and an abundance of aggregated α-syn has recently been demonstrated in both the healthy and PD appendix. However, the molecular changes that enable gut α-syn aggregates to con...
ORGANISM(S): Homo sapiens (Human) 
2020-02-18 | PXD015079 | Pride
Appendix Neurons Autophagy Lysosome Parkinson’s disease Epigenetic 
TranscriptomicscirDNA methylome analysis in prostate cancer
DNA modification profiling of circulating DNA (cirDNA) from plasma samples from prostate cancer patients (T2-3N0Mx), benign prostatic hyperplasia and control individuals Epigenetic differences are a common feature of many diseases, including cancer, and disease-associated changes have even been dete...
ORGANISM(S): Homo sapiens 
2012-07-09 | E-GEOD-36195 | biostudies-arrayexpress
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