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ProteomicsCK1 promotes double-strand break repair in fission yeast
CK1 enzymes are conserved, acidophilic serine/threonine kinases with a variety of critical cellular functions; their misregulation contributes to cancer, neurodegenerative diseases, and sleep phase disorders. The C-termini of these enzymes are thought to inhibit kinase activity by acting as pseudosu...
ORGANISM(S): Schizosaccharomyces pombe 
2025-05-06 | PXD033223 | Pride
Casein kinase 1 Ck1 Kinase substrates S. pombe Kinase regulation 
TranscriptomicsIdentification of New Branch Points and Unconventional Introns in Saccharomyces cerevisiae
Spliced messages constitute one-fourth of expressed mRNAs in the yeast Saccharomyces cerevisiae, and most mRNAs in metazoans. Splicing requires 5' splice site (5'SS), branch point (BP), and 3' splice site (3'SS) elements, but the role of the BP in splicing control is poorly understood because BP id...
ORGANISM(S): Saccharomyces cerevisiae S288c 
2016-08-01 | E-GEOD-68022 | biostudies-arrayexpress
TranscriptomicsGene expression profiles mas5D, ssa2D, hsf1-overexpressing and heat-stressed wild type Schizosaccharomyces pombe cells
The cells with the impaired Hsp40/Hsp70 chaperone complex Mas5/Ssa2 exhibit a transriptional response that is simillar to that of cells with the elevated levels of the heat-shock factor 1 (Hsf1) or heat-stressed wild type fission yeast cells A total of 6 experimental conditions has been analyzed inc...
ORGANISM(S): Schizosaccharomyces pombe 
2013-09-20 | E-GEOD-50156 | biostudies-arrayexpress
TranscriptomicsSexual Dimorphic Regulation of Liver Gene Expression by Glucocorticoids
Males and females exhibit differences in the incidence of many major diseases including auto-immune diseases, hepatocellular carcinoma, diabetes, and osteoporosis, which all have important inflammatory components in their etiology. Glucocorticoids are the primary physiological anti-inflammatory horm...
ORGANISM(S): Rattus norvegicus 
2010-10-01 | E-GEOD-13461 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Mycobacterium avium subspecies paratuberculosis Types I, II and III genomes by pan-genome microarray analysis
Data is also available from http://bugs.sgul.ac.uk/E-BUGS-69
ORGANISM(S): Mycobacterium avium 
2009-01-16 | E-BUGS-69 | biostudies-arrayexpress
UnknownReproducibility of quantitative myocardial perfusion and coronary flow capacity by positron emission tomography: 3D digital silicon photomultiplier solid state vs. legacy 2D analogue systems for clinical practice and trials.
Not available
S-EPMC11651154 | biostudies-literature
UnknownSchizosaccharomyces pombe Git7p, a member of the Saccharomyces cerevisiae Sgtlp family, is required for glucose and cyclic AMP signaling, cell wall integrity, and septation.
Not available
S-EPMC118005 | biostudies-literature
UnknownThe DNA Damage Repair Function of Fission Yeast CK1 Involves Targeting Arp8, a Subunit of the INO80 Chromatin Remodeling Complex.
Not available
S-EPMC11583621 | biostudies-literature
TranscriptomicsTranscription profiling of Staphylococcus aureus following inhibition of early-stage cell-wall biosynthesis
Data is also available from http://bugs.sgul.ac.uk/E-BUGS-71
ORGANISM(S): Staphylococcus aureus 
2009-01-27 | E-BUGS-71 | biostudies-arrayexpress
TranscriptomicsThree-dimensional disorganisation of the cancer genome occurs coincident with long range genetic and epigenetic alterations [RNA-seq]
A three-dimensional chromatin state underpins the structural and functional basis of the genome by bringing regulatory elements and genes into close spatial proximity to ensure proper, cell-type specific gene expression profiles. Here, we perform HiC chromosome conformation, ChIP-seq and RNA-seq to ...
ORGANISM(S): Homo sapiens 
2016-04-04 | E-GEOD-73784 | biostudies-arrayexpress
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