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When plants are exposed to non-freezing low temperatures, they can increase their freezing tolerance (cold acclimation, CA). Changes of plasma membrane (PM) and sterol/sphingolipid-enriched microdomain proteins are thought to be crucial for acquisition of freezing tolerance. Particularly, glycosylph...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2016-07-29 | PXD002908 | Pride
A proteomics strategy was used to identify putative GPI-APs from adult B. malayi. Three different sample types were prepared for analysis. Firstly, intact adult worms were treated with PI-PLC to enzymatically release and solubilize the protein away from the lipid moiety. A mock-treatment with no P...
ORGANISM(S): Brugia malayi 
2019-11-12 | PXD014949 | Pride
To clarify the selective advantage of the GPI-AP- cells in paroxysmal nocturnal hemoglobinuria (PNH) patients, RNA-seq was applied to examine functional effects of the PIG-A mutation in human granulocytes.
ORGANISM(S): Homo sapiens 
2016-04-09 | GSE80062 | GEO
The glycosylphosphatidylinositol (GPI) biosynthetic pathway in the endoplasmic reticulum (ER) is crucial for generating GPI-anchored proteins (GPI-APs), which are translocated to the cell surface and play a vital role in cell signaling and adhesion. This study focuses on two integral components of t...
ORGANISM(S): Mus musculus 
2024-05-19 | GSE266153 | GEO
Glycosylphosphatidylinositol anchored proteins (GPI-APs) in the outer leaflet of the membrane microdomains, commonly referred to as lipid rafts, play important roles in many biological processes. To enable large-scale site-specific analysis of GPI anchoring, we developed a method for identification ...
ORGANISM(S): Homo sapiens (Human) 
2016-05-27 | PXD003105 | Pride
Whole transcriptome sequencing identifies increased CXCR2 expression in PNH granulocytes
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