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GenomicsDNA sequence-dependent heterochromatin microdomain formation
DNA sequence-dependent heterochromatin microdomain formation
PRJNA666407 | ENA
ProteomicsErythrocyte Membrane Microdomains
Cholesterol-rich microdomains are membrane dynamic compartments characterized by specific lipid and protein composition and present in all cell types. These assemblies are involved in several biological processes, including infection by intracellular pathogens. This work provides a comprehensive ana...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-11-05 | MSV000086413 | MassIVE
ProteomicsExtensive proteomic approaches to identify glycosylphosphatidylinositol-anchored proteins in Arabidopsis reveal their diverse responses to cold acclimation
When plants are exposed to non-freezing low temperatures, they can increase their freezing tolerance (cold acclimation, CA). Changes of plasma membrane (PM) and sterol/sphingolipid-enriched microdomain proteins are thought to be crucial for acquisition of freezing tolerance. Particularly, glycosylph...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2016-07-29 | PXD002908 | Pride
Arabidopsis Plasma membrane Detergent-resistant membrane Microdomain Gpi-anchored protein Apoplast Freezing tolerance Cold acclimation 
GenomicsDNA sequence-dependent heterochromatin microdomain formation
Cell-type specific gene expression programs are established by distinct chromatin state patterns that involve thousands of heterochromatin microdomains of ~1-2 kb in size marked by di- and trimethylation of histone H3 at lysine 9 (H3K9me2/me3). However, no theoretical framework exists to predict the...
ORGANISM(S): Mus musculus 
2022-02-07 | GSE158744 | GEO
GenomicsPERM1 Gene Therapy Prevents Pressure Overload-induced Heart Failure Through a Sarcomere-Mitochondria Energetic Microdomain
PERM1 Gene Therapy Prevents Pressure Overload-induced Heart Failure Through a Sarcomere-Mitochondria Energetic Microdomain
PRJNA1493251 | ENA
ProteomicsCryoEM architecture of a near-native stretch-sensitive membrane microdomain
Eisosomes, stress-sensitive membrane compartments in yeast, are scaffolded by the BAR-domain proteins Pil1 and Lsp1. We isolated near-native eisosomes as helical filaments of Pil1/Lsp1 lattice bound to plasma membrane lipids and solved their structure by helical reconstruction. From the same near-na...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-07-18 | PXD050326 | Pride
Membrane microdomain Eisosome Pil1 Lsp1 
GenomicsThe intrinsically disordered AR2 microdomain of RNase E binds mRNA translation initiation regions
The intrinsically disordered AR2 microdomain of RNase E binds mRNA translation initiation regions
PRJNA1415097 | ENA
UnknownCoarse-grained modeling of annexin A2-induced microdomain formation on a vesicle.
Not available
S-EPMC11365106 | biostudies-literature
TranscriptomicsPERM1 Gene Therapy Prevents Pressure Overload-induced Heart Failure Through a Sarcomere-Mitochondria Energetic Microdomain
Heart failure with reduced ejection fraction (HFrEF) is characterized by impaired contractile function and mitochondrial dysfunction, yet therapies that simultaneously restore cardiac energetics and mechanical performance remain limited. Here, we demonstrate that adeno-associated virus (AAV)-mediate...
ORGANISM(S): Mus musculus 
2026-09-30 | GSE338319 | GEO
UnknownIntegrative visualization of the molecular structure of a cellular microdomain.
Not available
S-EPMC9926476 | biostudies-literature
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