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ProteomicsIdentification of GRAF1 interactome mediated by GRAF1 phosphorylation in response to Mitophagy
Defects in the clearance of dysfunctional mitochondria contribute to the development of heart failure and several neurological disorders including Parkinson’s disease (PD). The mitophagic signaling pathways that control the rapid recognition, ubiquitin-tagging and encasement of dysfunctional mitocho...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD043212 | Pride
Heart Graf1 Pink1-parkin pathway Mitophagy 
UnknownGRAF1 promotes ferlin-dependent myoblast fusion.
Not available
S-EPMC4535172 | biostudies-literature
UnknownGRAF1 deficiency leads to defective brown adipose tissue differentiation and thermogenic response.
Not available
S-EPMC11577055 | biostudies-literature
UnknownGRAF1 integrates PINK1-Parkin signaling and actin dynamics to mediate cardiac mitochondrial homeostasis.
Not available
S-EPMC10713658 | biostudies-literature
UnknownThe endocytic protein GRAF1 is directed to cell-matrix adhesion sites and regulates cell spreading.
Not available
S-EPMC3216663 | biostudies-literature
UnknownThe GTPase-activating protein GRAF1 regulates the CLIC/GEEC endocytic pathway.
Not available
S-EPMC2726289 | biostudies-literature
UnknownGRAF1 forms a complex with MICAL-L1 and EHD1 to cooperate in tubular recycling endosome vesiculation.
Not available
S-EPMC4214196 | biostudies-literature
UnknownEndocytic membrane turnover at the leading edge is driven by a transient interaction between Cdc42 and GRAF1.
Not available
S-EPMC4712783 | biostudies-literature
UnknownCdc42 Couples T Cell Receptor Endocytosis to GRAF1-Mediated Tubular Invaginations of the Plasma Membrane.
Not available
S-EPMC6912536 | biostudies-literature
UnknownSkeletal muscle differentiation and fusion are regulated by the BAR-containing Rho-GTPase-activating protein (Rho-GAP), GRAF1.
Not available
S-EPMC3138304 | biostudies-literature
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