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ProteomicsYeast response to protein misfolding induced by azetidine-2-carboxylic acid (AZC)
To identify proteins that interact with the yeast Tsa1 peroxiredoxin, we utilized an N-terminal Myc-tagged version of Tsa1 with a mutation in its resolving cysteineresidue (Tsa1-C171S) to trap and detect redox-dependent interactions. Yeast cells were left untreated, or treated with AZC or hydrogen p...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-09-10 | PXD023668 | Pride
Yeast Protein misfolding Peroxiredoxin 
ProteomicsYeast eIF4G homogenic whole cell oxidative stress LC-MSMS
Translation initiation factor 4G (eIF4G) is an integral component of the eIF4F complex which is key to translation initiation for most eukaryotic mRNAs. Many eIF4G isoforms have been described in diverse eukaryotic organisms but we currently have a poor understanding of their functional roles and wh...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-10-24 | PXD041682 | Pride
Lc-msms Yeast S. cerevisiae Oxidative stress Whole cell 
TranscriptomicsTranscription profiling of fission yeast cell cycle, cdc25 block and release 1
Cell cycle program in fission yeast using the temperature sensitive mutant cdc25-22
ORGANISM(S): Schizosaccharomyces pombe 
2009-01-20 | E-MEXP-57 | biostudies-arrayexpress
OtherThe yeast La related protein Slf1p is a key activator of translation during the oxidative stress response.
Data from ProteomeXchange, PXD ID: PXD000887. File: 20131025_GP_CK_S2_1in10_01.mzml. Published as part of PLoS Genet. 2015 Jan 8;11(1):e1004903 . From the Abstract: {{i}} The mechanisms by which RNA-binding proteins control the translation of subsets of mRNAs are not yet clear. Slf1p and Sro9p are ...
ORGANISM(S): Yeast 
GPM32310018418 | GPMDB
Resource Reanalysis 
Genomics2013-11-19-17-24-36-breez-MB-2013-10-18-Whole_exome_DNAseq_Medulloblastoma - samples
Illumina HiSeq sequence data (with >80x coverage) were aligned to the hg19 human reference genome assembly using BWA (Li and Durbin, 2009); duplicate reads were removed from the final BAM file. No realignment or recalibration was performed. The whole exome sequencing data of 20 SHH medulloblastomas ...
EGAD00001000698 | EGA
UnknownClinical and Demographic Factors Associated With COVID-19, Severe COVID-19, and SARS-CoV-2 Infection in Adults: A Secondary Cross-Protocol Analysis of 4 Randomized Clinical Trials.
Not available
S-EPMC10346130 | biostudies-literature
UnknownNo clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.
Not available
S-EPMC4630206 | biostudies-literature
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