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Immunoaffinity enrichemt of GREB1 to co-enrich HSP90
ORGANISM(S): Homo sapiens (Human) 
2018-05-02 | PXD008631 | Pride
A distinct feed-forward mechanism between GREB1 and steroid receptors dictates hormone-dependent GREB1 action in endometrial function and dysfunction
Estrogen receptor-alpha (ER) is the driving transcription factor in most breast cancers, and its associated proteins can influence drug response, but direct methods for identifying interacting proteins have been limited. We purified endogenous ER using an approach termed RIME (rapid immunoprecipitat...
ORGANISM(S): Homo sapiens (Human) 
2013-08-09 | PXD000047 | Pride
GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance
The cellular responses to the steroid hormones, estrogen (E2), and progesterone (P4) are governed by their cognate receptor’s transcriptional output. Although multiple mechanisms including the tissue-specific coactivators dictate these transcriptional signatures, the feed-forward mechanisms, that ev...
ORGANISM(S): Homo sapiens 
2024-02-14 | GSE254175 | GEO
GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance
GREB1, a novel target of Wnt signaling, promotes development of hepatoblastoma by suppressing TGFβ signaling
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