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UnknownHydroxycarbamide Plus Aspirin Versus Aspirin Alone in Patients With Essential Thrombocythemia Age 40 to 59 Years Without High-Risk Features.
Not available
S-EPMC6269131 | biostudies-literature
TranscriptomicsRegulation of Lifespan, Metabolism, and Stress Responses by the Drosophila SH2B Protein, Lnk
Drosophila Lnk is the single ancestral orthologue of a highly conserved family of structurally-related intracellular adaptor proteins, the SH2B proteins. As adaptors, they lack catalytic activity but contain several protein-protein interaction domains, thus playing a critical role in signal transduc...
ORGANISM(S): Drosophila melanogaster 
2016-03-30 | E-MTAB-4612 | biostudies-arrayexpress
ProteomicsSox9 accelerates vascular ageing by regulating extracellular matrix composition and stiffness
Vascular calcification and increased extracellular matrix (ECM) stiffness are hallmarks of vascular ageing. Sox9 (SRY-Box Transcription Factor 9) is a master regulator of chondrogenesis, also expressed in the vasculature, that has been implicated in vascular smooth muscle cell (VSMC) osteo-chondroge...
ORGANISM(S): Homo sapiens (Human) 
2024-06-16 | PXD046001 | Pride
Vascular smooth muscle cells Sox9 Extracellular matrix Senescence 
TranscriptomicsTranscriptional profiling of cumulus cells differentiation throughout oocyte competence acquisition in the bovine ovarian follicles.
Somatic cells surrounding the oocyte were sampled at the following stages: developmentally incompetent or poorly competent prophase I oocytes (NC1 oocytes), developmentally competent prophase I oocytes (C1 oocytes), and developmentally competent metaphase II oocytes (C2 oocytes). NC1 cumulus cells (...
ORGANISM(S): Bos taurus 
2012-10-14 | E-GEOD-36605 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of somatic cells differentiation throughout oocyte competence acquisition in the xenopus ovarian follicles.
Somatic cells surrounding the oocyte were sampled at the following stages: developmentally incompetent or poorly competent prophase I oocytes (NC1 oocytes), developmentally competent prophase I oocytes (C1 oocytes), and developmentally competent metaphase II oocytes (C2 oocytes). NC1 samples were co...
ORGANISM(S): Xenopus laevis 
2012-10-14 | E-GEOD-36603 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of somatic cells differentiation throughout oocyte competence acquisition in rainbow trout ovarian follicles.
Somatic cells surrounding the oocyte were sampled at the following stages: developmentally incompetent or poorly competent prophase I oocytes (NC1 oocytes), developmentally competent prophase I oocytes (C1 oocytes), and developmentally competent metaphase II oocytes (C2 oocytes). NC1 samples were co...
ORGANISM(S): Oncorhynchus mykiss 
2012-10-14 | E-GEOD-36602 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of cumulus cells differentiation throughout oocyte competence acquisition in the murine ovarian follicles.
Cumulus cells surrounding the oocyte were sampled at the following stages: developmentally incompetent or poorly competent prophase I oocytes (NC1 oocytes), developmentally competent prophase I oocytes (C1 oocytes), and developmentally competent metaphase II oocytes (C2 oocytes). NC1 samples were co...
ORGANISM(S): Mus musculus 
2012-10-14 | E-GEOD-36604 | biostudies-arrayexpress
TranscriptomicsDeregulated expression programs in the hypomorphic Dnmt3b mutant mice
The function of Dnmt3b, of which deregulated activity is linked to several human pathologies, was studied using Dnmt3b hypomorphic mutant mice with reduced catalytic activity. Microarray analysis of deregulated expression programs in the hypomorphic Dnmt3b mutant mice (m3/m24) was combined to an ana...
ORGANISM(S): Mus musculus 
2010-04-21 | E-GEOD-19597 | biostudies-arrayexpress
TranscriptomicsGenetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predispose to myeloproliferative neoplasms
Genome-wide association study of JAK2 V617F negative myeloproliferative neoplasms consisting of 524 cases at stage 1
ORGANISM(S): Homo sapiens 
2015-02-20 | E-MTAB-3340 | biostudies-arrayexpress
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