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ProteomicsCompetition-based, quantitative chemical proteomics in breast cancer cells identifies new target profiles for sulforaphane
Sulforaphane is a small molecule isothiocyanate which exhibits anticancer potential, yet its biological targets remain poorly understood. Here we employ a competition-based chemical proteomics strategy to profile sulforaphane’s targets and identify over 500 targets along with their relative affiniti...
ORGANISM(S): Homo sapiens (Human) 
2017-05-24 | PXD006279 | Pride
Sulforaphane  cancer  chemical proteomics 
UnknownReconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig.
Not available
S-EPMC7002414 | biostudies-literature
UnknownBREATHER Plus clinical trial design: A randomised non-inferiority trial evaluating the efficacy, safety and acceptability of short cycle (five days on, two days off) dolutegravir/tenofovir-based triple antiretroviral therapy (ART) compared to daily ART in virologically suppressed adolescents living with HIV aged 12 to <20 years in sub-Saharan Africa.
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S-EPMC7617909 | biostudies-literature
UnknownA catalog of genetic loci associated with kidney function from analyses of a million individuals.
Not available
S-EPMC6698888 | biostudies-literature
UnknownDisease burden attributable to intimate partner violence against females and sexual violence against children in 204 countries and territories, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.
Not available
S-EPMC12775558 | biostudies-literature
UnknownMapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000-2018.
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S-EPMC9760541 | biostudies-literature
UnknownGlobal age-sex-specific all-cause mortality and life expectancy estimates for 204 countries and territories and 660 subnational locations, 1950-2023: a demographic analysis for the Global Burden of Disease Study 2023.
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S-EPMC12535839 | biostudies-literature
UnknownGlobal burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.
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S-EPMC12535838 | biostudies-literature
UnknownBurden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.
Not available
S-EPMC12535840 | biostudies-literature
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