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TranscriptomicsXenobiotics shape the physiology and gene expression of the active human gut microbiome
The human gut is colonized by trillions of microorganisms that influence human health and disease through the metabolism of xenobiotics, including therapeutic drugs and antibiotics. The diversity and metabolic potential of the human gut microbiome have been extensively characterized, but it remains ...
ORGANISM(S): human gut metagenome 
2012-10-30 | E-GEOD-38151 | biostudies-arrayexpress
TranscriptomicsWhole-genome methylation analysis (450k) of school aged children prenatally exposed to alcohol vs controls
We tested a hypothesis that prenatal alcohol exposure may lead to epigenetic alterations to the DNA resulting in attentional and cognitive alterations of the children. 6-9 year old children school children of the Franconian Cognition and Emotion Studies (FRANCES) cohort which were tested for an obj...
ORGANISM(S): Homo sapiens 
2018-05-12 | E-MTAB-6730 | biostudies-arrayexpress
TranscriptomicsMaternal Influence on Exonic CpG Island Methylation in the Developing Hippocampus
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-02-04 | E-GEOD-35856 | biostudies-arrayexpress
TranscriptomicsConsequences of conceptus exposure to colony stimulating factor 2 on survival, elongation, interferon-{tau} secretion and gene expression
Exposure of bovine conceptuses to colony stimulating factor 2 (CSF2) from Day 5 to 7 of development can increase the percent of transferred conceptuses that develop to term. The purpose of this experiment was to understand the mechanism by which CSF2 increases embryonic and fetal survival. Conceptus...
ORGANISM(S): Bos taurus 
2011-12-15 | E-GEOD-26842 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of phenylepherine response in rat neonatal ventricular myocytes
Title: Regulation of gene expression through mitogen-activated protein kinase cascades in cardiac myocytes.
Description: We aim to identify the changes in gene expression induced in rat
neonatal ventricular myocytes, a well established cell culture model,
by phenylepherine, ...
ORGANISM(S): Rattus norvegicus 
2006-10-01 | E-MIMR-37 | biostudies-arrayexpress
TranscriptomicsTranscriptional profile asm gene cluster of high Ansamitocin P3 producing mutants derived from A. pretiosum
This series of microarry is the study of the transcriptional profile asm gene clusster of high Ansamitocin P3 producing mutants derived from isolating rifampicin resistant mutants. Background The Actinomycete Actinosynnema pretiosum ssp. auranticum has commercial importance due to its production o...
ORGANISM(S): Actinosynnema pretiosum 
2008-12-01 | E-GEOD-12739 | biostudies-arrayexpress
TranscriptomicsDivergent gene-expression profiles between proepicardium and epicardium differentiation
The HH16/17 chicken proepicardium (PE) gives rise to the embryonic epicardium (Epi) which significantly contributes formation of the coronary vasculature during cardiac development. In contrast to explanted Epi cells, explanted PE cells can undergo differentiation into a cardiac myocyte phenotype. I...
ORGANISM(S): Gallus gallus 
2010-12-21 | E-GEOD-13923 | biostudies-arrayexpress
TranscriptomicsMolecular profiling of single circulating tumor cells with diagnostic intention
About 230 clinical trials currently explore the role of circulating tumor cell (CTC) analysis for therapy decisions, but no assays enable comprehensive molecular characterization of CTCs with diagnostic precision. We therefore combined a workflow for CTC enrichment and isolation with 100% purity wit...
ORGANISM(S): Homo sapiens 
2014-11-05 | E-GEOD-58192 | biostudies-arrayexpress
TranscriptomicsGlobal transcriptional profiling in porcine liver and lymph node tissues during acute pleuropneumoni
Expression profiles of porcine liver and tracheobronchial lung lymph node tissues were studied to identify genes being significantly affected by bacterial infection of the lungs. Samples were taken from liver and tracheobronchial lung lymph node tissues in pigs experimentally infected with A. pleuro...
ORGANISM(S): Sus scrofa 
2013-01-01 | E-GEOD-16038 | biostudies-arrayexpress
TranscriptomicsThe regenerative response in the pig liver remnant varies with the degree of resection and rise in portal pressure.
Following parenchymal loss, the liver regenerates restoring normal mass and metabolic function. Prevailing theories on triggering events leading to regeneration include humoral, metabolic and flow-mediated mechanisms, the latter emphasizing the importance of shear stress mediated nitric oxide (NO) r...
ORGANISM(S): Sus scrofa 
2008-01-14 | E-GEOD-6860 | biostudies-arrayexpress
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