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TranscriptomicsChemosensitization of DLBCL cells in vitro and in vivo by demethylating nucleoside analogues [methylation]
Silencing of genes that suppress the malignant phenotype by DNA methylation spurred an interest in the clinical use of epigenetic reprogramming agents. Single therapy is unlikely to be curative in the context of a heterogeneous disease such as Diffuse Large B cell Lymphomas (DLBCL). The combination ...
ORGANISM(S): Homo sapiens 
2012-07-29 | E-GEOD-31101 | biostudies-arrayexpress
UnknownPhase I/II study of the antibody-drug conjugate glembatumumab vedotin in patients with advanced melanoma.
Not available
S-EPMC4879709 | biostudies-literature
TranscriptomicsSessile serrated adenomas and conventional adenomas of the colon
Sessile serrated adenomas are now recognized as precursor lesions of a substantial subset of colorectal cancers arising via a so-called “serrated pathway”. However, their biological markers remain to be defined. The aim of our study was to identify differentially expressed genes in sessile serrated ...
ORGANISM(S): Homo sapiens 
2008-08-26 | E-GEOD-12514 | biostudies-arrayexpress
TranscriptomicsChemosensitization of DLBCL cells in vitro and in vivo by demethylating nucleoside analogues
This SuperSeries is composed of the following subset Series: GSE28744: Chemosensitization of DLBCL cells in vitro and in vivo by demethylating nucleoside analogues [gene expression] GSE31101: Chemosensitization of DLBCL cells in vitro and in vivo by demethylating nucleoside analogues [methylation] R...
ORGANISM(S): Homo sapiens 
2012-07-29 | E-GEOD-31104 | biostudies-arrayexpress
ProteomicsCocaine and Environmental Enrichment Proteomics Study of Rat Nucleus Accumbens
Prior research demonstrated that environmental enrichment creates individual differences in behavior leading to a protective addiction phenotype in rats. Understanding the mechanisms underlying this phenotype will guide selection of targets for much-needed novel pharmacotherapeutics. The current stu...
ORGANISM(S): Rattus norvegicus (Rat) 
2014-07-22 | PXD000990 | Pride
Rat Brain Nucleus accumbens Lc-ms/ms Label-free quantification 
TranscriptomicsBurkitt Lymphoma Pathogenesis and Therapeutic Targets from Structural and Functional Genomics
Burkitt lymphoma (BL) can often be cured by intensive chemotherapy, but the toxicity of such therapy precludes its use in the elderly and in patients with endemic BL (eBL) in developing countries, necessitating new strategies. The normal germinal center B cell is the presumed cell of origin for both...
ORGANISM(S): Homo sapiens 
2012-08-16 | E-GEOD-35163 | biostudies-arrayexpress
TranscriptomicsMethylation profiles of Chronic kidney disease
Epidemiological studies indicate that adverse intrauterine and postnatal environment has a long-lasting role in chronic kidney disease (CKD) development. Epigenetic information can represent a plausible carrier for mediating this "programming" effect. Here we demonstrate that genome-wide c...
ORGANISM(S): Homo sapiens 
2013-08-09 | E-GEOD-49557 | biostudies-arrayexpress
TranscriptomicsInduction of the IL-9 gene by HTLV-I Tax stimulates the spontaneous proliferation of primary adult T-cell leukemia cells
The mechanism whereby IL-9 stimulated monocytes, promote proliferation of co-cultured ATL cells remains undefined. To obtain preliminary clues concerning this contribution, transcription profiles were obtained between monocytes derived from ATL patients and those derived from healthy donors as asses...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-10789 | biostudies-arrayexpress
UnknownDevelopment and Validation of a Short Version of the Metric for the Observation of Decision-Making in Multidisciplinary Tumor Boards: MODe-Lite.
Not available
S-EPMC8519835 | biostudies-literature
UnknownNavigating the Ophthalmology & Urology Match with a Significant Other.
Not available
S-EPMC9792430 | biostudies-literature
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