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To determine whether the inhibition of DOT1L (EPZ-5675) affects the enrichment of components within specific non-canonical PRC1 (ncPRC1) complexes, we performed rapid immunoprecipitation mass spectrometry of endogenous protein (RIME) of BCOR (ncPRC1.1) and PCGF6 (ncPRC1.6) for human GCB-DLBCL cell l...
ORGANISM(S): Homo sapiens (Human) 
2026-10-19 | PXD061504 | Pride
The Androgen Receptor (AR) is a ligand-dependent transcription factor that drives prostate cancer development and progression. Although, a detailed effect on AR biology has been described for a number of interacting proteins, many AR coregulators remain to be characterized in relation to their disti...
ORGANISM(S): Homo sapiens (Human) 
2025-06-16 | PXD058914 | Pride
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