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GenomicsSulfurovum sp. AR strain:AR
Draft genome sequence of Sulfurovum sp. strain AR
PRJDB84 | ENA
GenomicsPaenarthrobacter sp. AR 02 strain:AR 02
Paenarthrobacter sp. AR 02 strain:AR 02 Genome sequencing and assembly
PRJNA785363 | ENA
GenomicsChIP-seq study using a cell line model of ER_ AR+ molecular apocrine tumours (AR_FoxA1_molecular_apocrine)
Breast cancer is a heterogeneous disease and several distinct subtypes exist based on differential gene expression patterns. Molecular apocrine tumours were recently identified as an additional subgroup, characterised as oestrogen receptor negative and androgen receptor positive (ER_ AR+), but with ...
ORGANISM(S): Homo sapiens 
2012-02-18 | E-MTAB-986 | biostudies-arrayexpress
GenomicsGenome-wide analysis of SUMOylation effects on androgen receptor (AR) binding in PC-3 cells (ChIP-seq)
Androgen receptor (AR) plays an important regulatory role during prostate cancer development. ARM-bM-^@M-^Ys transcriptional activity is regulated by androgenic ligands, but also by post-translational modifications. To study the role of the AR SUMOylation in genuine chromatin environment, we compare...
ORGANISM(S): Homo sapiens 
2014-07-03 | E-GEOD-54110 | biostudies-arrayexpress
GenomicsGenome-wide analysis of SUMOylation effects on androgen receptor (AR) binding in HEK293 cells (ChIP-seq)
Androgen receptor (AR) plays an important regulatory role during prostate cancer development. ARM-bM-^@M-^Ys transcriptional activity is regulated by androgenic ligands, but also by post-translational modifications. To study the role of the AR SUMOylation in genuine chromatin environment, we compare...
ORGANISM(S): Homo sapiens 
2014-07-03 | E-GEOD-54109 | biostudies-arrayexpress
GenomicsNext Generation Sequencing Facilitates Quantitative Analysis of effect of knockdown of GATA2 on AR binding sites
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study are to compare AR binding activity in LNCaP cells with and without knockdown of GATA2. Methods: LNCaP cells between passage number 32-34 were used for assay. Cells are tr...
ORGANISM(S): Homo sapiens 
2014-01-21 | E-GEOD-52725 | biostudies-arrayexpress
TranscriptomicsGATA2 facilitates steroid receptor coactivator (SRC) recruitment to the androgen receptor (AR) complex
The androgen receptor (AR) is a key driver of prostate cancer (PC), even in the state of castration-resistant PC (CRPC), and frequently even after treatment with second-line hormonal therapies such as abiraterone and enzalutamide. The persistence of AR activity via both ligand-dependent and ligand-i...
ORGANISM(S): Homo sapiens 
2015-01-21 | E-GEOD-63539 | biostudies-arrayexpress
MetabolomicsSpermine is a natural suppressor of AR signaling in castration-resistant prostate cancer
In castration-resistant prostate cancer (CRPC), clinical response to androgen receptor (AR) antagonists is limited mainly due to AR-variants expression and restored AR signaling. The metabolite spermine is most abundant in prostate and it decreases as prostate cancer progresses, but its functions re...
2023-10-11 | MTBLS8034 | MetaboLights
ProteomicsAR RIME in Human Prostate Cancer Cells
BPTF, the scaffolding subunit of the nucleosome remodeling factor (NURF) complex, has been implicated in the progression of several malignancies, but its role in prostate cancer (PCa) remains unclear. Here, we demonstrate that BPTF is upregulated in castration-resistant prostate cancer (CRPC) and pr...
ORGANISM(S): Homo sapiens (Human) 
2025-11-19 | PXD070903 | Pride
Ar Human prostate cancer cell Rv1 
ProteomicsGNL3 orchestrates AR transcriptional programs to drive castration-resistant prostate cancer and immune evasion
Androgen receptor (AR) signaling is a primary oncogenic driver of castration-resistant prostate cancer (CRPC), yet the mechanism remains incompletely understood. Dysregulation of the AR co-regulatory network has emerged as a key driver of castration resistance. To identify AR-interacting proteins li...
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD067138 | Pride
Castration-resistant prostate cancer Ar coregulator Immunosuppression Gnl3 
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