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TranscriptomicsSmad4 and Trim33 dependend nodal/activin responsive genes in differentiated mouse ESCs
In differentiated mouse ESCs, most of the nodal/activin responsive genes are dependent on both Smad4 and Trim33, some are solely dependent on Smad4, and some are dependent on Trim33. Ebs at Day2.5 from WT, Smad4 null, and Trim33 knock-down ESCs, were treated with activin or SB 431542 for 2 h.
ORGANISM(S): Mus musculus 
2012-01-09 | E-GEOD-32903 | biostudies-arrayexpress
ProteomicsTRIM33 loss reduces Androgen Receptor transcriptional output and H2BK120 ubiquitination
The Androgen Receptor (AR) is a ligand-dependent transcription factor that drives prostate cancer development and progression. Although, a detailed effect on AR biology has been described for a number of interacting proteins, many AR coregulators remain to be characterized in relation to their disti...
ORGANISM(S): Homo sapiens (Human) 
2025-06-16 | PXD058914 | Pride
Ar Trim33 Rime Lc-msms 
GenomicsGenomewide mapping of Trim33 binding in Th17 cells
Genomewide mapping of Trim33 binding in Th17 cells
PRJNA464365 | ENA
ProteomicsA role for the Trim33 ubiquitin ligase in cellular response to replicative stress
Deregulation of RNA polymerase II (RNAPII) by oncoproteins, such as transcription factor Myc, interferes with DNA replication and is a major source of DNA damage and genomic instability. Ubiquitination is a key pathway controlling RNAPII activity via modification of RNAPII subunits or associated re...
ORGANISM(S): Mus musculus (Mouse) 
2023-07-24 | PXD037854 | Pride
Ap. ap-ms. lc-ms. ubiquitination. trim33. e2f4. stress response 
GenomicsGenome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation [Trim33 RNA-Seq]
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation [Trim33 RNA-Seq]
PRJNA1081402 | ENA
GenomicsThe Trim33 ubiquitin ligase limits E2f4-dependent DNA replication [DSB]
The Trim33 ubiquitin ligase limits E2f4-dependent DNA replication [DSB]
PRJNA899471 | ENA
UnknownTumour suppressor TRIM33 targets nuclear β-catenin degradation.
Not available
S-EPMC4315364 | biostudies-literature
UnknownTrim33 mediates the proinflammatory function of Th17 cells.
Not available
S-EPMC6028517 | biostudies-literature
UnknownMacrophage production and activation are dependent on TRIM33.
Not available
S-EPMC5354896 | biostudies-literature
GenomicsTRIM33 deficiency in mature myeloid cells impairs resolution of colonic inflammation
TRIM33 deficiency in mature myeloid cells impairs resolution of colonic inflammation
PRJNA513468 | ENA
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