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UnknownMutational Spectrum, Copy Number Changes, and Outcome: Results of a Sequencing Study of Patients With Newly Diagnosed Myeloma.
Not available
S-EPMC6485456 | biostudies-literature
TranscriptomicsGene profiling of TRA1 and tra1-L3733A
Tra1 is a component of the Saccharomyces cerevisiae SAGA and NuA4 complexes and a member of the phosphatidylinositol 3-kinase kinase family that contain a C-terminal PI3K domain followed by a 35-residue FATC domain. We analyzed alleles with single residue changes in the FATC domain. Of these tra1-L3...
ORGANISM(S): Saccharomyces cerevisiae 
2010-09-19 | E-GEOD-18591 | biostudies-arrayexpress
TranscriptomicsWnt/Ca2+/NFAT signaling maintains survival of Ph+ leukemia cells upon inhibition of Bcr-Abl
Although Bcr-Abl kinase inhibitors have proven effective in the treatment of chronic myeloid leukemia (CML), they generally fail to completely eradicate Bcr-Abl+ leukemia cells. To identify genes whose inhibition sensitizes Bcr-Abl+ leukemias to killing by Bcr-Abl inhibitors, we performed an RNAi-ba...
ORGANISM(S): Homo sapiens 
2010-07-15 | E-GEOD-21499 | biostudies-arrayexpress
UnknownAssociation of Cell-Free DNA Tumor Fraction and Somatic Copy Number Alterations With Survival in Metastatic Triple-Negative Breast Cancer.
Not available
S-EPMC5815405 | biostudies-literature
TranscriptomicsTranscription profiling of human lung tissue from emphysema and control patients
Gene expression profiling of lung tissue from undiseased (NML), 'usual' emphysema (EML), and Alpha-1 Antitrypsin Deficiency-related emphysema (ADL).
ORGANISM(S): Homo sapiens 
2007-07-19 | E-GEOD-1122 | biostudies-arrayexpress
UnknownPatient and family perceptions of telehealth as part of the cystic fibrosis care model during COVID-19.
Not available
S-EPMC7997421 | biostudies-literature
MetabolomicsA metabolomic study of adipose tissue in mice with a disruption of the circadian system

Adipose tissue functions in terms of energy homeostasis as a rheostat for blood triglyceride, regulating its concentration, in response to external stimuli. In addition it acts as a barometer to inform the central nervous system of energy levels which can vary dramatically between meals and accor...

2017-10-27 | MTBLS390 | MetaboLights
TranscriptomicsMicroarray data from YTHDF2-deficient pre-leukemic cells and control pre-leukemic cells
YTHDF2 is overexpressed in a broad spectrum of human acute myeloid leukemias (AML). To study the role of YTHDF2 in leukemia, c-Kit+ cells from foetal livers of Ythdf2fl/fl;Vav-iCre (Ythdf2CKO) and Ythdf2fl/fl (Ythdf2CTL) 14.5 dpc embryos were transduced with Meis1 and Hoxa9 oncogenes and serially re...
ORGANISM(S): Mus musculus 
2019-04-05 | E-MTAB-6783 | biostudies-arrayexpress
UnknownRandomized Phase II Evaluation of Bevacizumab Versus Bevacizumab Plus Fosbretabulin in Recurrent Ovarian, Tubal, or Peritoneal Carcinoma: An NRG Oncology/Gynecologic Oncology Group Study.
Not available
S-EPMC4962710 | biostudies-literature
TranscriptomicsTranscription profiling of mouse Cftr knockout or wild type colonic epithelial cells treated with rosiglitazone
30-day-old Cftr-/- homozygous for the S489X, B6.129P2-Cftr(tm1Unc), mutation or sibling wild-type control mice were treated with standard chow or 20 mg/kg/d rosiglitazone for 5 days. Colonic epithelial cells were extracted and mRNA isolated. Cftr-/- mice suffer from a severe intestinal phenotype inc...
ORGANISM(S): Mus musculus 
2010-03-19 | E-MTAB-188 | biostudies-arrayexpress
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