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UnknownA low alpha-linolenic intake during early life increases adiposity in the adult guinea pig.
Not available
S-EPMC2825514 | biostudies-literature
UnknownIn vitro modulation of multidrug resistance by pregnane steroids and in vivo inhibition of tumour development by 7α-OBz-11α(R)-OTHP-5β-pregnanedione in K562/R7 and H295R cell xenografts.
Not available
S-EPMC6383615 | biostudies-literature
UnknownDistribution of innate efflux-mediated aminoglycoside resistance among different Achromobacter species.
Not available
S-EPMC4726742 | biostudies-literature
UnknownDiversity of innate immune cell subsets across spatial and temporal scales in an EAE mouse model.
Not available
S-EPMC5865173 | biostudies-literature
UnknownCytomegalovirus Infection of the Rat Developing Brain In Utero Prominently Targets Immune Cells and Promotes Early Microglial Activation.
Not available
S-EPMC4966896 | biostudies-literature
TranscriptomicsBroad and largely overlapping molecular changes arise in thymic and peripheral XCR1+ dendritic cells upon tolerogenic and immunogenic maturation
This SuperSeries is composed of the SubSeries listed below. DC were isolated from lymphoid organs as previously described (Vremec et al., 2000). DC subsets were sorted by flow cytometry according to the marker combinations described in the 'characteristics: phenotype' field for each sample for each ...
ORGANISM(S): Mus musculus 
2016-08-22 | E-GEOD-71171 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of human iPSC-derived Neural Stem Cells (NSC) from LCA patients and unaffected persons
Our purpose was to investigate genes and molecular mechanisms involved in patients with Leber congenital amaurosis (LCA). Fibroblasts from two unrelated clinically-identified patients (Coriell) were reprogrammed to pluripotency by retroviral transduction. These human induced Pluripotent Stem Cells (...
ORGANISM(S): Homo sapiens 
2015-01-21 | E-GEOD-43924 | biostudies-arrayexpress
TranscriptomicsHuman induced pluripotent stem cells reveal early developmental molecular correlates with a probable Leber congenital amaurosis type I
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-01-21 | E-GEOD-43946 | biostudies-arrayexpress
ProteomicsMultiomics analyses reveal B cell differentiation arrest and neutrophil hypogranulation in a patient with an immunodeficiency caused by a novel homozygous missense variant in HYOU1
The Hypoxia Upregulated Protein 1 (HYOU1) encodes an endoplasmic reticulum chaperone which is expressed in response to endoplasmic reticulum stress and contributes to cellular protection by restoring cell homeostasis. In this study, we report a patient with a novel homozygous variant in HYOU1 (NM_00...
ORGANISM(S): Homo sapiens (Human) 
2026-08-18 | PXD058947 | Pride
B cell deficiency Multiomics Neutrophil hypogranulation Hyou1 Immunodeficiency 
TranscriptomicsGene expression profiling of mouse spleen XCR1+ DC at steady state, 3 hours after polyI:C or 12 hours after STAg i.v. injection
The goal of this experiment was to use global gene expression profiling to compare the global genetic reprogramming of spleen XCR1+ DC upon in vivo stimulation with a viral-type ligand, polyI:C which strongly induces type I interferons, versus with a ligand derived from an intracellular parasite whi...
ORGANISM(S): Mus musculus 
2016-08-22 | E-GEOD-71168 | biostudies-arrayexpress
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