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ProteomicsMC4 crosslinking of rhodopsin and GRK1 complex
G protein-coupled receptor (GPCR) kinases (GRKs) selectively phosphorylate agonist bound GPCRs, thereby switching the signal from G protein-dependent to arrestin-dependent pathways, including receptor internalization and downregulation. There are currently no high-resolution details known about how ...
ORGANISM(S): Bos taurus (Bovine) 
2021-07-15 | PXD019215 | Pride
Mc4 Grk1 Rhodopsin Crosslinking Gpcr Rhodopsin kinase 
UnknownNew variants and in silico analyses in GRK1 associated Oguchi disease.
Not available
S-EPMC7898643 | biostudies-literature
UnknownA novel missense mutation of the GRK1 gene in Oguchi disease.
Not available
S-EPMC5042745 | biostudies-literature
UnknownNeovascularization, enhanced inflammatory response, and age-related cone dystrophy in the Nrl-/-Grk1-/- mouse retina.
Not available
S-EPMC3055752 | biostudies-literature
UnknownDeletion of PrBP/delta impedes transport of GRK1 and PDE6 catalytic subunits to photoreceptor outer segments.
Not available
S-EPMC1885592 | biostudies-literature
UnknownSpecies-specific differences in expression of G-protein-coupled receptor kinase (GRK) 7 and GRK1 in mammalian cone photoreceptor cells: implications for cone cell phototransduction.
Not available
S-EPMC6763890 | biostudies-literature
UnknownNeuronal Calcium Sensor-1 Binds the D2 Dopamine Receptor and G-protein-coupled Receptor Kinase 1 (GRK1) Peptides Using Different Modes of Interactions.
Not available
S-EPMC4513130 | biostudies-literature
TranscriptomicsGinsenoside RK1 Promotes Hepatic Stellate Cell Glycolysis-Mediated Ferroptosis by Activating the HK2/ACSL4/LPCAT3/ALOX5 Signaling Pathway
Liver fibrosis (LF) is a pathological condition that if not controlled can progress into liver sclerosis and malignant tumors. Ferroptosis has been comprehensively studied and found to improve LF by exacerbating hepatic cell ferroptosis. Ginsenoside RK1 (GRK1) is an essential component of ginseng wi...
ORGANISM(S): Rattus norvegicus 
2026-06-01 | GSE299196 | GEO
UnknownStructure of a monomeric variant of rhodopsin kinase at 2.5 A resolution.
Not available
S-EPMC3370896 | biostudies-literature
GenomicsGinsenoside RK1 Promotes Hepatic Stellate Cell Glycolysis-Mediated Ferroptosis by Activating the HK2/ACSL4/LPCAT3/ALOX5 Signaling Pathway
Ginsenoside RK1 Promotes Hepatic Stellate Cell Glycolysis-Mediated Ferroptosis by Activating the HK2/ACSL4/LPCAT3/ALOX5 Signaling Pathway
PRJNA1273054 | ENA
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