Rhodopsin - OmicsDI

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UNIPROT ID/AC

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Metabolite Name

[4-phenyl-5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl]methanamine (1)
[(1S,7S,8S,8aS)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,4,4a,7,8,8a-octahydronaphthalen-1-yl] (2S)-2-methylbutanoate (1)
Tenivastatin sodium (1)
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N-{1-[(6-ethoxy-3-pyridyl)methyl]tetrahydro-1H-pyrrol-3-yl}-2-(3-pyridyl)acetamide (1)
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H-Phe-phe-OH (1)
H-Leu-ile-OH (1)
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H-Glu-Tyr-OH (1)
Guanosine Monophosphate (1)

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Modelling Approach

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Lab affiliation

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IsPrivate

False (3)

Classification

bacteria (3)
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Study type

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Release Date

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2000 (4)
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1997 (2)

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MC4 crosslinking of rhodopsin and GRK1 complex

G protein-coupled receptor (GPCR) kinases (GRKs) selectively phosphorylate agonist bound GPCRs, thereby switching the signal from G protein-dependent to arrestin-dependent pathways, including receptor internalization and downregulation. There are currently no high-resolution details known about how ...

ORGANISM(S): Bos taurus (Bovine)

2021-07-15 | PXD019215 | Pride

Proteome analysis of the retina from RhoQ344X/+ mouse

Retinal proteomes from wild-type and RhoQ344X mutant mice at postnatal day 35 were analyzed by label-free quantitative proteomics to understand proteomic change caused by the rhodopsin mutation.

ORGANISM(S): Mus Musculus (ncbitaxon:10090)

2023-11-08 | MSV000093339 | MassIVE

RNA-Seq of Xenopus laevis Retina after Crispr-mediated Rhodopsin depletion

PRJEB73582 | ENA

CRISPRi mediated treatment of dominant rhodopsin-associated retinitis pigmentosa.

PRJNA1024894 | ENA

Network biology analysis of P23H rhodopsin interactome identifies protein and mRNA quality control mechanisms

Rhodopsin is essential for phototransduction, and many rhodopsin mutations cause heritable retinal degenerations. The P23H rhodopsin variant generates a misfolded rhodopsin protein that photoreceptors quickly target for degradation by mechanisms that are incompletely understood. To gain insight in...

ORGANISM(S): Mus Musculus (ncbitaxon:10090)

2022-08-24 | MSV000090197 | MassIVE

RNA-Seq of Xenopus laevis Retina after Crispr-mediated Rhodopsin depletion

In Xenopus laevis knocking out rhodopsin genes by crispr/Cas9 is a model of Retinitis pigmentosa. In late tadpole (permissive stages), glial Muller cells proliferate to support a regeneration response in the retina. However in early tadpole (refractory stages) the proliferative response is absent an...

ORGANISM(S): Xenopus laevis

2025-02-02 | E-MTAB-13881 | biostudies-arrayexpress

RNAseq analysis of the global retinal transcriptome of rhodopsin knockout mice

We report RNAseq analysis of the transcriptome of retinas from mature rhodopsin knockout mice

ORGANISM(S): Mus musculus

2016-12-31 | GSE61239 | GEO

miRNA Expression analysis from genomic form of Rhodopsin DNA Nanoparticles treated P23H Knock-in Heterozygous Mouse (P23H+/-)

PRJNA641357 | ENA

Lipid-rhodopsin hydrophobic mismatch alters rhodopsin helical content.

Not available

S-EPMC2538621 | biostudies-literature

Rhodopsin 7-The unusual Rhodopsin in Drosophila.

Not available

S-EPMC5018682 | biostudies-literature

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