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TranscriptomicsTranscription profiling of rat heart and adipose tissue response to aging and caloric restriction in
Sustained caloric restriction (CR) extends lifespan in animal models but the mechanism and primary tissue target(s) have not been identified. Gene expression changes with aging and CR were examined in both heart and subcutaneous white adipose tissue (WAT) of F344 male rats using Affymetrix® RAE 230...
ORGANISM(S): Rattus norvegicus 
2008-06-15 | E-GEOD-6718 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat organ of Corti (OC), modiolus (MOD) and stria vascularis (SV) of newborns
The aim of this study was to characterize the basal expression of OC, MOD and SV of newborn rats (3-5 day old) and its changes by short–term cultivation (24 hrs) and mild hypoxia (5 hrs). Three varieties of tissue samples were analyzed (i) Freshly prepared tissue, used as control; (ii) cultures he...
ORGANISM(S): Rattus norvegicus 
2008-06-13 | E-GEOD-5446 | biostudies-arrayexpress
UnknownDraft Genome Sequence of the Sattazolin-Producing Strain Pseudonocardia sp. C8, Isolated from a Mud Dauber Wasp Nest in Nepal.
Not available
S-EPMC7953278 | biostudies-literature
UnknownDraft Genome Sequence of Nonomuraea sp. Strain C10, a Producer of Brartemicin, Isolated from a Mud Dauber Wasp Nest in Nepal.
Not available
S-EPMC6838623 | biostudies-literature
TranscriptomicsGene expression based analysis of Streptococcus uberis 0140J and vru (sub0144) mutant
Comparison of bacterial strains S. uberis 0140J with isogenic mutant (same strain) with lesion 5 basepairs upstream of ATG start codon of the vru or sub0144 gene. Bacteria were grown in stationary culture in THB media at 37C with triplicate samples extracted at early exponential (OD550 =0.42) at lat...
ORGANISM(S): Streptococcus uberis 
2012-06-30 | E-GEOD-33186 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of Blochmannia floridanus during different host stages
The transcriptome of Blochmannia floridanus, the endosymbiont of the carpenter ant Camponotus floridanus, is presented during eight developmental stages of its holometabolous host by use of a whole genome DNA-macroarray. The detected transcription patterns indicate the presence of local transcriptio...
ORGANISM(S): Candidatus Blochmannia floridanus 
2008-11-09 | E-GEOD-12148 | biostudies-arrayexpress
TranscriptomicsThe NuA4 complex promotes Translesion Synthesis (TLS) - mediated DNA damage tolerance
DNA lesions can block a replication fork, leading to its collapse and gross chromosomal rearrangements. To circumvent such outcomes, DNA damage tolerance (DDT) pathways become engaged, allowing the replisome to bypass the lesion and complete S phase in the presence of unrepaired damage. Here we demo...
ORGANISM(S): Saccharomyces cerevisiae 
2015-02-21 | E-GEOD-66176 | biostudies-arrayexpress
TranscriptomicsmicroRNA alterations associated to early relapse in advanced stage ovarian cancer patients (validation set)
A set of 45 surgical specimens has been profiled for miRNA expression to validate miRNA alterations associated to early relapse in advanced stage ovarian cancer patients. Fresh frozen samples were collected from a series of consecutive patients with high-grade advanced stage ovarian cancer who under...
ORGANISM(S): Homo sapiens 
2015-04-30 | E-GEOD-67819 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat fetal kidney samples from offspring of hyperinsulinemic mothers
Inrauterine growth restriction was induced by chronic hyper insulinemia in pregnant rats and differential gene expression was studied using affymetrix rat genome RAE230A.Data was analysed using SAM. Experiment Overall Design: rna was isolated from 5 kidneys of growth restricted fetus and compared wi...
ORGANISM(S): Rattus norvegicus 
2007-11-06 | E-GEOD-3215 | biostudies-arrayexpress
TranscriptomicsAnalysis of gene expression profiles from the liver of rats treated with the mitochondrial electron transport chain complex III inhibitor GSK932121A (50mg/kg) or vehicle control
BACKGROUND: Correlating in vitro mitochondrial data to outcomes in vivo remains a challenge and improving methods to assess mitochondrial function in vivo would both guide safer candidate selection and support the growing number of discovery programmes targeting mitochondria for pharmacological inte...
ORGANISM(S): Rattus norvegicus 
2015-01-29 | E-GEOD-65374 | biostudies-arrayexpress
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