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TranscriptomicsSpatial and Temporal Regulation of Gene Expression in the Mammalian Growth Plate
To explore the mechanisms responsible for spatial and temporal regulation of the growth plate, we microdissected postnatal rat growth plates into their constituent zones and then used microarray analysis to characterize the changes in gene expression that occur as chondrocytes undergo spatially-asso...
ORGANISM(S): Rattus norvegicus 
2010-02-22 | E-GEOD-16981 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human growth plate chondrocytes were isolated from the distal femoral growth plate from 3 different adolescents undergoing epiphysiodesis
Human growth plate chondrocytes were isolated from the distal femoral growth plate from 3 different adolescents undergoing epiphysiodesis. Cell were isolated and grown in monolayers, long term, in 20% serum. Cells were replated and cultured 48 h in 0.5% serum.
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-1278 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human growth plate chrondrocytes grown in monolayer, 0.5 vs. 20% serum
Human growth plate chondrocytes were isolated from the distal femoral growth plate from a single adolescent undergoing epiphysiodesis. Cell were isolated and grown in monolayers, long term. Cells were replated and cultured in 0.5% or 20% serum.
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-1277 | biostudies-arrayexpress
TranscriptomicsFetal mesenchymal stromal cells differentiating towards chondrocytes acquire a gene expression profile resembling human growth plate cartilage.
We used human fetal bone marrow-derived mesenchymal stromal cells (hfMSCs) differentiating towards chondrocytes as an alternative model for the human growth plate (GP). Our aims were to study gene expression patterns associated with chondrogenic differentiation to assess whether chondrocytes derived...
ORGANISM(S): Homo sapiens 
2013-04-22 | E-GEOD-40942 | biostudies-arrayexpress
TranscriptomicsExpression data from articular and growth plate cartilage
The aim of the current study was to identify molecular markers for articular cartilage that can be used for the quality control of tissue engineered cartilage. Therefore a genom-wide expression analysis was performed using RNA isolated from articular and growth plate cartilage, both extracted from t...
ORGANISM(S): Sus scrofa 
2011-07-28 | E-GEOD-23492 | biostudies-arrayexpress
MetabolomicsEndophytic mycobiont provides growth benefits via a Phenylpropanoid-Auxin axis in host plants

Beneficial association with symbiotic fungi helps improve the growth and fitness in most land plants, and shows great potential as biofertilizers in precision agriculture. Here, we demonstrated that a root fungal endophyte, Tinctoporellus species isolate AR8, enabled yield improvement in...

2025-04-11 | MTBLS12374 | MetaboLights
ProteomicsPhysical and chemical niche of human growth plate for polarized bone development
The significantly enriched proteins in growth plate-epiphysis interface compared to growth plate and epiphysis and the significantly enriched proteins in growth plate-metaphysis interface compared to growth plate and metaphysis;
ORGANISM(S): Homo Sapiens 
2025-01-16 | PXD059908 |
MetabolomicsSalmonella Modulates Metabolism during Growth under Conditions that Induce Expression of Virulence Genes
Salmonella enterica serovar Typhimurium (S. Typhimurium) is a facultative pathogen that uses complex mechanisms to invade and proliferate within mammalian host cells. To investigate possible contributions of metabolic processes to virulence in S. Typhimurium grown under conditions known to induce ex...
2013-05-02 | MTBLS35 | MetaboLights
ProteomicsSpatial lipidomic profiling of mouse joint tissue demonstrates the essential role of PHOSPHO1 in growth plate homeostasis
Lipids play a crucial role in signalling and metabolism, regulating the development and maintenance of the skeleton. Membrane lipids have been hypothesised to act as intermediates upstream of orphan phosphatase 1 (PHOSPHO1), a major contributor to phosphate generation required for bone mineralisatio...
ORGANISM(S): Mus musculus (Mouse) 
2023-04-19 | PXD038909 | Pride
Mouse Maldi-ims Phospho1 Matrix mineralisation Disorders of calcium or phosphate metabolism Lipids Knee joint Growth plate Bone modelling and remodelling 
MetabolomicsLimosilactobacillus reuteri in Promoting Growth Performance and Regulating Lipid Metabolism in Zuili Black Pigs

Abstract

Background

The gut microbiota is a key regulator of host lipid metabolism. In indigenous pigs, variation in growth performance and intramuscular fat (IMF) deposition has been linked to microbiota-host interactions, yet the specific taxa and metabolites that govern host lipid ...

2025-09-20 | MTBLS13017 | MetaboLights
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