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ProteomicsNLRC5 IP-MS in neonatal mouse cardiomyocyte lysates
The neonatal mouse cardiomyocytes (NMCMs) lysate was immunoprecipitated using either IgG (control) or anti-NLRC5 antibody. Immunoprecipitated samples were subjected to SDS-PAGE followed by high-throughput LC/MS to identify the candidate interacting proteins of NLRC5.
ORGANISM(S): Mus musculus (Mouse) 
2025-05-06 | PXD051371 | Pride
Immunoprecipitation Nlrc5 Mass spectrometry 
TranscriptomicsA Global Genomic View of MIF Knockdown Cell
siRNA-mediated knockdown of MIF expression in HEK293 cells resulted in inhibition of cell proliferation and cell cycle progress. The microarray study of MIF KD cells reveald knockdown of MIF would lead to extensive changes in gene expression profiles which may elucidate the molecular mechanism of...
ORGANISM(S): Homo sapiens 
2009-11-02 | E-GEOD-10241 | biostudies-arrayexpress
MetabolomicsAcupuncture Synergized With Bortezomib Improves Survival of Multiple Myeloma Mice via Decreasing Metabolic Ornithine
Multiple myeloma (MM) is a hematological malignancy worldwide in urgent need for novel therapeutic strategies. Since Velcade (bortezomib) was approved for the treatment of relapsed/refractory MM in 2003, we have seen considerable improvement in extending MM patient survival. However, most patients a...
2022-02-21 | MTBLS3487 | MetaboLights
ProteomicsCDK9 binds and activates SGK3 to promote cardiac repair after injury via the GSK-3β/β-catenin pathway
SGK3 (threonine-protein kinase 3) is a functional kinase we identified previously with the capacity to promote cardiomyocyte proliferation and cardiac repair after myocardial infarction. However, the upstream signals regulating SGK3 are still unknown. Based on the quantitative proteomics data and pu...
ORGANISM(S): Mus Musculus 
PXD035187 |
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