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In this study, through naïve nanobody phage library screening, we have identified multiple nanobodies against human YAP with high affinity and specificity. The YAP nanobody was then fused to the RING domain of RNF4, creating a bio-Proteolysis-Targeting Chimera (bioPROTAC) molecule capable of selecti...
ORGANISM(S): Homo sapiens (Human) 
2025-11-03 | PXD063726 | Pride
Spatial metabolomics describes the location and chemistry of small molecules involved in metabolic phenotypes, defense molecules and chemical interactions in natural communities. Most current techniques are unable to spatially link the genotype and metabolic phenotype of microorganisms in situ at a ...
2019-11-15 | MTBLS746 | MetaboLights

Lipids are an integral part of cellular membranes, vary between species, and allow cells to alter stiffness, permeability and curvature. Among lipids, phosphonolipids uniquely contain a phosphonate bond between carbon and phosphorous. Despite this distinctive biochemical characteristic, few model...

2022-06-26 | MTBLS2960 | MetaboLights
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