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TranscriptomicsTranscription profiling of rat fibroblasts transformed with HRAS and treated with the demethylating agent 5-aza-2-deoxycytidine
Silencing of gene expression by methylation of CpG islands in regulatory elements is frequently observed in cancer. However, an influence of the most common oncogenic signalling pathways onto DNA methylation has not yet been investigated thoroughly. To address this issue, we identified genes suppres...
ORGANISM(S): Rattus norvegicus 
2007-11-06 | E-GEOD-4427 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of rat cortex regions
The neocortex of the mammalian brain is comprised by six distinct layers with neuronal subtypes that appear indistinguishable from one cortical area to the next. Correspondingly, global gene expression seems to be almost identical across the cerebral cortex and only a few genes have so far been repo...
ORGANISM(S): Rattus norvegicus 
2010-12-31 | E-TABM-1019 | biostudies-arrayexpress
GenomicsGenomic DNA T b. brucei and T. b. rhodesiense. Data for E-MTAB-3800
Genomic DNA T b. brucei and T. b. rhodesiense. These are actually paired reads but the files are unpaired
ORGANISM(S): Trypanosoma brucei 
2021-12-17 | E-MTAB-11303 | biostudies-arrayexpress
TranscriptomicsThe transcriptome of TRPV1-positive sensory neurons revealed by subgroup-elimination transcriptomics
We developed an approach to rapidly eliminate the subgroup of sensory neurons expressing the heat-gated cation channel TRPV1 from dissociated rat sensory ganglia using agonist treatment followed by density centrifugation. To identify transcripts predomintly expressed in TRPV1-positive neurons, we co...
ORGANISM(S): Rattus norvegicus 
2015-05-12 | E-GEOD-59727 | biostudies-arrayexpress
TranscriptomicsImmunomodulatory Effects of Massage on Non-Perturbed Skeletal Muscle in Rats
Microarray was used as a screening tool to determine changes in gene transcription with cyclic compressive loading (CCL) (massage mimetic) applied at varying magnitudes in non-perturbed skeletal muscle. 24 male Wistar Rats were randomly assigned to one of three groups based on magnitude of load: Con...
ORGANISM(S): Rattus norvegicus 
2013-09-01 | E-MEXP-3957 | biostudies-arrayexpress
TranscriptomicsRat infection with Trypanosoma rhodesiense clinical isolates
Rats (four per isolate) were infected with Trypansooma rhodesiense taken from the CNS of two different patients from Lwala. Blood was taken at parasitaemias ranging from 3-20 E7. The results can be compared with those from human patient samples.
ORGANISM(S): Rattus norvegicus 
2017-12-30 | E-MTAB-6125 | biostudies-arrayexpress
MetabolomicsA multiplatform metabolomic approach to characterize fecal signatures of stressful postnatal events in chicks: a pilot study
Negative experiences in early life can induce long-lasting effects on the welfare, health, and performance of farm animals. A delayed placement of chicks in breeding houses has negative effects on their performance, and results in fecal-specific odours detectable by rats. Based on this observation, ...
2019-04-11 | MTBLS763 | MetaboLights
TranscriptomicsGlucocorticoid and androgen receptor profiling (ChIP-seq) in U2OS-GR and U2OS-AR cells upon hormone treatment
We performed ChIP-seq targeting the glucocorticoid receptor (GR) in the U2OS-GR cell line and the androgen receptor (AR) in the U2OS-AR cell line. The cell lines are derived from U2OS ATTC:HTB-96 and stably transfected with an expression construct for either rat GR or human AR, respectively. The U2O...
ORGANISM(S): Homo sapiens 
2021-03-09 | E-MTAB-9616 | biostudies-arrayexpress
TranscriptomicsTranscriptomes of bloodstream-form trypanosomes from culture or buffy coat
Poly(A)+ RNA was sequenced from various trypanosome isolates grown either in culture, or in rats.
ORGANISM(S): Trypanosoma brucei 
2015-12-01 | E-MTAB-3793 | biostudies-arrayexpress
TranscriptomicsTemporal Changes in Rat Liver Gene Expression after Acute Cadmium and Chromium Exposure
U.S. Service Members and civilians are at risk of exposure to a variety of environmental health hazards throughout their normal duty activities and in industrial occupations. Metals are widely used in large quantities in a number of industrial processes and are a common environmental toxicant, which...
ORGANISM(S): Rattus norvegicus 
2015-05-21 | E-GEOD-65198 | biostudies-arrayexpress
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