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TranscriptomicsExpression profiling of B.subtils SMY wild-type, (p)ppGpp0, M-NM-^TcodY (p)ppGpp0 and guaB- (p)ppGpp0 cells upon amino acid starvation (RHX) or guanosine (Guo) treatment.
The nucleotide (p)ppGpp is crucial for viability during amino acid limitation in bacteria, yet how it accomplishes this remains unknown. We found that the absence of (p)ppGpp in Bacillus subtilis cells leads to multiple amino acid auxotrophy, and that (p)ppGpp allows for prototrophy by reducing GTP ...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2013-11-01 | E-GEOD-41501 | biostudies-arrayexpress
GenomicsMetastasis-repressive CircRNA MASCOT Regulates Distribution of the Splicing Factor hnRNP M
Metastasis-repressive CircRNA MASCOT Regulates Distribution of the Splicing Factor hnRNP M
PRJNA694988 | ENA
MetabolomicsUntargeted metabolomics profiling reveals exercise intensity-dependent alterations in Thoroughbred racehorses’ plasma after routine conditioning sessions

Thoroughbred (TB) racehorses are subjected to rigorous conditioning programs involving exercise sessions of various types, distances and intensities. These programs aim to optimize both their physical and mental capabilities, which are essential to achieve maximal performance. Conventional invest...

2024-01-16 | MTBLS8285 | MetaboLights
ProteomicsProteomics of necrotic granulomas in lungs of C3HeB/FeJ mice infected with M. tuberculosis
C3heB/FeJ mice were infected with M. tuberculosis to form necrotic granulomatous lesions. FFPE samples of infected lungs with granulomas were microdissected into three distinct regions, Caseum, foamy macrophage, and Cell. Proteins were extracted from microdissected samples, followed by LC-MS/MS.
ORGANISM(S): Mus Musculus (mouse) 
2022-09-06 | PXD030088 | JPOST Repository
UnknownInsight into the phylogeny and metabolic divergence of Monascus species (M. pilosus, M. ruber, and M. purpureus) at the genome level.
Not available
S-EPMC10249731 | biostudies-literature
TranscriptomicsShort telomeres compromise M-NM-2-cell signaling and survival
The factors that underlie the increasing incidence of diabetes with age are poorly understood. We examined whether telomere length, known to decrease with age, plays a role in the age-dependent increased incidence of diabetes. We show that in mice with short telomeres, insulin secretion is impaire...
ORGANISM(S): Mus musculus 
2013-10-01 | E-GEOD-25040 | biostudies-arrayexpress
TranscriptomicsGene expression in an EMT model using an immortalized bronchial epithelial cell line induced by TGF-M-NM-21
This study aimed to establish an epithelial-mesenchymal transition (EMT) model with an immortalized human bronchial epithelial cell line, M-BE, and to identify an EMT signature gene set. The TGF-M-NM-21-induced M-BE cells got spindle-shaped fibroblast-like morphology and lost the cell-cell contact, ...
ORGANISM(S): Homo sapiens 
2013-10-06 | E-GEOD-40374 | biostudies-arrayexpress
GenomicsIdentification of transcription factor binding sites from ChIP-seq data at high-resolution
Genome-wide mapping of proteinM-bM-^@M-^SDNA interactions is essential for a full understanding of transcriptional regulation. A precise map of binding sites for transcription factors, core transcriptional machinery is vital for deciphering the gene regulatory networks that underlie various biologic...
ORGANISM(S): Drosophila melanogaster 
2014-02-06 | E-GEOD-40664 | biostudies-arrayexpress
UnknownBare and ligand protected planar hexacoordinate silicon in SiSb3M3 + (M = Ca, Sr, Ba) clusters.
Not available
S-EPMC9278486 | biostudies-literature
GenomicsMLL3 Loss Drives Metastasis by Promoting a Hybrid Epithelial-Mesenchymal Transition State [RNA-seq EM vs M]
MLL3 Loss Drives Metastasis by Promoting a Hybrid Epithelial-Mesenchymal Transition State [RNA-seq EM vs M]
PRJNA851733 | ENA
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