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UnknownChemical composition and pharmacological mechanism of Qingfei Paidu Decoction and Ma Xing Shi Gan Decoction against Coronavirus Disease 2019 (COVID-19): In silico and experimental study.
Not available
S-EPMC7194979 | biostudies-literature
MetabolomicsEffects of Radiofrequency Field from 5G Communications on fecal microbiome and metabolome profiles in mice

With the rapid development of 5G networks, the influence of the radiofrequency field (RF) generated from 5G communication equipment on human health are gathering increasing attention. This study aimed at assessing the effects of long-term exposure to 4.9 GHz (one of the working frequency of 5G co...

2022-11-08 | MTBLS4186 | MetaboLights
UnknownCase Report: Gefitinib in EGFR 19del recurrent aggressive fibromatosis.
Not available
S-EPMC12301188 | biostudies-literature
UnknownFluorescence enhanced lab-on-a-chip patterned using a hybrid technique of femtosecond laser direct writing and anodized aluminum oxide porous nanostructuring.
Not available
S-EPMC9418693 | biostudies-literature
MetabolomicsEvaluation of significant features discovered from different data acquisition modes in mass spectrometry-based untargeted metabolomics

Despite the growing popularity of liquid chromatography-mass spectrometry (LC-MS)-based metabolomics, no study has yet to systematically compare the performance of different data acquisition modes in the discovery of significantly altered metabolic features, which is an important task of untarget...

2020-10-02 | MTBLS1842 | MetaboLights
ProteomicsGMPS promoting tumor immune evasion by regulating the glycosylation modification of PD-L1
Hepatocellular carcinoma (HCC) is a malignant tumor characterized by rapid progression, whose development is attributed to severe immune evasion. Here, we conducted proteomic and scRNA-Seq analysis on advanced HCC tissues and identified a significant molecule, Guanine monophosphate synthase (GMPS). ...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-25 | PXD045485 | Pride
Ptm Hcc Pd-l1 Immunotherapy 
TranscriptomicsA histone H3.3 Lysine 36 Trimethylation Reader Connects Chromatin to Regulated Pre-mRNA Processing
BS69 (aka ZMYND11) was initially discovered as a direct target of adenoviral E1A oncoprotein1. Subsequent studies implicated BS69 as a tumor suppressor and a transcriptional regulator2. But exactly how BS69 regulates gene expression has remained elusive. BS69 contains tandemly arranged PHD, BROMO an...
ORGANISM(S): Homo sapiens 
2014-09-01 | E-GEOD-51261 | biostudies-arrayexpress
MetabolomicsTFAM loss induces nuclear actin assembly upon mDia2 malonylation to promote liver cancer metastasis
The mechanisms underlying cancer metastasis remain poorly understood. Here, we report that TFAM deficiency rapidly and stably induced spontaneous lung metastasis in mice with liver cancer. Interestingly, unexpected polymerization of nuclear actin was observed in TFAM-knockdown HCC cells when cytoske...
2022-06-23 | MTBLS4307 | MetaboLights
MetabolomicsMulti-omics integration analysis reveals metabolic changes during sika deer antler growth

Background: Antler is an important economic trait of sika deer (Cervus nippon), capable of rapid growth without signs of tumorigenesis. However, the molecular mechanisms underlying its unique growth pattern remain poorly understood. This study conducted a combined transc...

2026-04-01 | MTBLS12622 | MetaboLights
UnknownFunctional variants in the promoter region of Chitinase 3-like 1 (CHI3L1) and susceptibility to schizophrenia.
Not available
S-EPMC1785314 | biostudies-literature
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