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MetabolomicsHabitual Coffee Intake Shapes the Gut Microbiome and Modifies Host Physiology and Cognition

Coffee influences multiple physiological processes, including gut function, stress, cognition, and the microbiome. However, the mechanisms underlying these effects remain poorly understood. In this study, we examined coffee’s impact on the microbiota–gut–brain axis—a bidirectional communication p...

2026-04-07 | MTBLS13494 | MetaboLights
MetabolomicsHabitual Coffee Intake Shapes the Gut Microbiome and Modifies Host Physiology and Cognition: double-blind, randomised, parallel design

Coffee influences multiple physiological processes, including gut function, stress, cognition, and the microbiome. However, the mechanisms underlying these effects remain poorly understood. In this study, we examined coffee’s impact on the microbiota–gut–brain axis—a bidirectional communication p...

2026-03-26 | MTBLS13401 | MetaboLights
TranscriptomicsXenobiotics shape the physiology and gene expression of the active human gut microbiome
The human gut is colonized by trillions of microorganisms that influence human health and disease through the metabolism of xenobiotics, including therapeutic drugs and antibiotics. The diversity and metabolic potential of the human gut microbiome have been extensively characterized, but it remains ...
ORGANISM(S): human gut metagenome 
2012-10-30 | E-GEOD-38151 | biostudies-arrayexpress
MetabolomicsContribution of fungal microbiome to intestinal physiology, early-life immune development and mucosal inflammation in mice
The gut microbiome consists of a multi-kingdom microbial community. Whilst the role of bacteria as causal contributors governing host physiological development is well established, the role of fungi remains to be determined. Here, we use germ-free mice colonized with defined species of bacteria, fun...
2022-01-14 | MTBLS1679 | MetaboLights
TranscriptomicsMicroarray-based annotation of the gut transcriptome of the migratory locust, Locusta migratoria
The migratory locust, Locusta migratoria, is a serious agricultural pest and important insect model to study insect digestion and feeding behavior. The gut is one of the primary interfaces between the insect and its environment. Nevertheless, knowledge on the gut transcriptome of L. migratoria is st...
ORGANISM(S): Locusta migratoria 
2016-07-02 | E-GEOD-83967 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression analysis in adult rotation-resistant (RR) and wild-type (WT) western corn rootworm digestive tracts
The western corn rootworm (WCR, Diabrotica virgifera virgifera LeConte) is an important pest of corn (Zea mays) in the US. Annual crop rotation between corn and soybean (Glycine max) disrupts the corn-dependent WCR lifecycle and was widely adopted to manage WCR. However, this strategy selected for ...
ORGANISM(S): Diabrotica virgifera virgifera 
2015-11-23 | E-GEOD-62480 | biostudies-arrayexpress
ProteomicsGenome-resolved metaproteomic characterization of preterm infant gut microbiota development reveals core metabolic functions and variability during early-life
An integrated metagenomics and metaproteomics investigation of human preterm infant gut microbiota.
ORGANISM(S): Gut Microbiota Of Human Preterm Infants 
2017-02-23 | MSV000080565 | MassIVE
MetabolomicsInfluence of early life exposure, host genetics and diet on the mouse gut microbiome and metabolome
Although the gut microbiome plays important roles in host physiology, health and disease, we lack understanding of the complex interplay between host genetics and early life environment on the microbial and metabolic composition of the gut. We used the genetically diverse Collaborative Cross mouse s...
2016-10-05 | MTBLS345 | MetaboLights
MetabolomicsA defined community of core gut microbiota members promotes cognitive performance in honey bees

Gut microbiota across animals have been shown to influence host cognition and behavior. However, it remains unclear whether these cognitive effects are driven by specific bacterial species or arise from community-level interactions. Here, we leveraged the honey bee (Apis mellifera) as a ...

2026-05-21 | MTBLS13943 | MetaboLights
MetabolomicsIntegrated metabolomic and microbiomic analysis of the effects of dietary Candida utilis replacement of fishmeal on the growth, physiology, and intestinal microbiota of southern catfish (Silurus meridionalis)

Liver samples of southern catfish were sent to Majorbio Bio-pharm Technology Co., Ltd. for untargeted metabolomic sequencing referring to previous study [27]. Grinding beads were added to the liver samples, and metabolites were extracted via low-tempe...

2025-11-19 | MTBLS13346 | MetaboLights
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