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TranscriptomicsPYR/PYL receptors play a major role for regulation of transcriptional response to abscisic acid
Abscisic acid (ABA) is a key hormone for plant growth, development and stress adaptation. Perception of ABA through four types of receptors has been reported. We show here that impairment of ABA perception through the PYR/PYL/RCAR branch reduces vegetative growth and seed production, and leads to a ...
ORGANISM(S): Arabidopsis thaliana 
2012-11-30 | E-GEOD-36692 | biostudies-arrayexpress
MetabolomicsAccumulation of the coumarin scopolin under abiotic stress conditions is mediated by the Arabidopsis thaliana THO/TREX complex
Secondary metabolites are involved in the plant stress response. Among these are scopolin and its active form scopoletin, which are coumarin derivatives associated with reactive oxygen species scavenging and pathogen defence. Here we show that in Arabidopsis thaliana, scopolin accumulation can be in...
2018-02-05 | MTBLS389 | MetaboLights
MetabolomicsProtein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase

Metabolic networks are interconnected and influence diverse cellular processes. The protein-metabolite interactions that mediate these networks are frequently low affinity and challenging to systematically discover. We developed mass spectrometry integrated with equilibrium dialysis for the disco...

2023-08-07 | MTBLS7237 | MetaboLights
ProteomicsSplicing Factor SRSF1 Deficiency in the Liver Triggers NASH-like Pathology via R-Loop Induced DNA Damage and Cell Death
Regulation of RNA processing contributes profoundly to tissue development and physiology. The serine-arginine-rich splicing factor 1 (SRSF1) is essential for hepatocyte function and survival. Although SRSF1 is mainly known for its many roles in mRNA metabolism, it is also crucial for maintaining gen...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD027035 | Pride
Srsf1 Liver Hepatocyte Splicing 
UnknownSurvival After Invasive or Conservative Management of Stable Coronary Disease.
Not available
S-EPMC9797439 | biostudies-literature
UnknownFactors Associated With Coronary Angiography Performed Within 6 Months of Randomization to the Conservative Strategy in the ISCHEMIA Trial.
Not available
S-EPMC11187765 | biostudies-literature
UnknownHeptavalent pneumococcal conjugate vaccine immunogenicity in very-low-birth-weight, premature infants.
Not available
S-EPMC2949965 | biostudies-literature
UnknownEvaluating the Appropriate Use Criteria for Coronary Revascularization in Stable Ischemic Heart Disease Using Randomized Data From the ISCHEMIA Trial.
Not available
S-EPMC11919559 | biostudies-literature
UnknownInitial Invasive or Conservative Strategy for Stable Coronary Disease.
Not available
S-EPMC7263833 | biostudies-literature
UnknownVariation in global trauma care: a survey of 187 hospitals across 51 countries.
Not available
S-EPMC12598983 | biostudies-literature
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