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High-fat diet (HFD) decreases insulin sensitivity. How high-fat diet causes insulin resistance is largely unknown. Here, we show that lean mice become insulin resistant after being administered exosomes isolated from the feces of obese mice fed a high-fat diet (HFD) or from human type II diabetic pa...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-23 | PXD022641 | Pride
In our study, We found that exosomal transfer occurred from highly metastatic nasopharyngeal carcinoma (NPC) cells to poorly metastatic NPC cells mediates cell-cell communication and therefore enhanced metastasis potential and decreased intracellular ROS levels of low metastatic NPC cells. To invest...
ORGANISM(S): Homo sapiens 
2020-05-02 | GSE149714 | GEO
Drug resistance frequently results in treatment failure for leukemia and leads to the progression of chronic myeloid leukemia (CML) into an accelerated or blast phase. Although new tyrosine kinase inhibitors (TKIs) and combined TKI therapies have been developed to address BCR-ABL1 mutation-induced d...
ORGANISM(S): Homo sapiens 
2026-02-13 | GSE318881 | GEO
Purpose: Although Nm23-H1 lacks secretion signal peptide, its presence in the extracellular space and extracellular vesicles (EVs) is widely reported. Proteomics profiling revealed that EVs released by cancer cells may contain Nm23-H1 proteins but the role of vesicular Nm23-H1 remains unknown. Here,...
ORGANISM(S): Homo sapiens 
2025-12-30 | GSE189685 | GEO
SCAP were collected from intact, caries-free impacted third molars with immature roots extracted from three healthy human patients (12–15 years of age). The cells were cultured to the 5th passage. Then, the supernatant was collected after 48 h of continuous culture in exosome-free serum medium (SBI,...
ORGANISM(S): Homo sapiens 
2026-04-08 | GSE272147 | GEO
Differential miRNA expression of healthy and inflammatory periodontal ligament stem cells-derived exosomes
We present the low-input ChIP-exo minimization (ChIP-mini) method, which is suitable for processing small bacterial cell numbers, as few as 4.8x10⁶ (bacterial culture volume: 10 µl). This method faithfully maintains the relevant binding profiles of Escherichia coli K-12 MG1655 RpoD, as generated by ...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium Escherichia coli K-12 
2025-02-05 | GSE252525 | GEO
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