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High-fat diet (HFD) decreases insulin sensitivity. How high-fat diet causes insulin resistance is largely unknown. Here, we show that lean mice become insulin resistant after being administered exosomes isolated from the feces of obese mice fed a high-fat diet (HFD) or from human type II diabetic pa...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-23 | PXD022641 | Pride
Cell layer-specific modification of cell wall is associated with exo-mesocarp split in pistachio (Pistacia vera L.)
We cataloged miRNA expression in the nucleus accumbens and at striatal synapses in control and chronically cocaine-treated mice. We identified cocaine-responsive miRNAs, synaptically-enriched and depleted miRNA families, and confirmed cocaine-induced changes in protein expression for several predict...
ORGANISM(S): Mus musculus 
This SuperSeries is composed of the following subset Series: GSE16183: Genome-Wide Promoter Analysis of Epigenetic Regulation by Cocaine (MM5 data) GSE16184: Genome-Wide Promoter Analysis of Epigenetic Regulation by Cocaine (MM8 data) Refer to individual Series
ORGANISM(S): Mus musculus 
Changes in miRNA profile of CD4+ T cells treated with cocaine 6 samples were analysed, 3 control and 3 treated with cocaine
ORGANISM(S): Homo sapiens 
Changes in gene expression contribute to the long-lasting regulation of the brain's reward circuitry seen in drug addiction, however, the specific genes regulated and the transcriptional mechanisms underlying such regulation remain poorly understood. Here, we used chromatin immunoprecipitation coupl...
ORGANISM(S): Mus musculus 
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