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GenomicsDynamic loss of H2B ubiquitylation without corresponding changes in H3K4 tri-methylation during myogenic differentiation
Ubiquitylation of H2B on lysine 120 (H2Bub) is associated with active transcriptional elongation. H2Bub has been implicated in histone cross-talk and is generally regarded to be a prerequisite for H3K4 and H3K79 tri-methylation in both yeast and mammalian cells. We performed a genome-wide analysis o...
ORGANISM(S): Mus musculus 
2012-03-06 | E-GEOD-34960 | biostudies-arrayexpress
GenomicsH3K4 tri-methylation provides an epigenetic signature of active enhancers
Combinations of post-translational histone modifications shape the chromatin landscape during cell development in eukaryotes. However, little is known about the modifications exactly delineating functionally engaged regulatory elements. For example, although histone H3 lysine 4 mono-methylation (H3K...
ORGANISM(S): Mus musculus 
2014-03-07 | E-GEOD-55635 | biostudies-arrayexpress
GenomicsGenome-wide mapping of H3K4 tri-methylation in ΔUvkmt2 mutant strain of Ustilaginoidea virens
Genome-wide mapping of H3K4 tri-methylation in ΔUvkmt2 mutant strain of Ustilaginoidea virens
PRJNA839430 | ENA
GenomicsDynamic loss of H2B ubiquitylation without corresponding changes in H3K4 tri-methylation during myogenic differentiation
Ubiquitylation of H2B on lysine 120 (H2Bub) is associated with active transcriptional elongation. H2Bub has been implicated in histone cross-talk and is generally regarded to be a prerequisite for H3K4 and H3K79 tri-methylation in both yeast and mammalian cells. We performed a genome-wide analysis o...
ORGANISM(S): Mus musculus 
2012-03-06 | GSE34960 | GEO
GenomicsSwd2/Cps35 determines H3K4 tri-methylation via interactions with Set1 and Rad6_H3K4me3 ChIPseq in WT and several strains
Swd2/Cps35 determines H3K4 tri-methylation via interactions with Set1 and Rad6_H3K4me3 ChIPseq in WT and several strains
PRJNA1085653 | ENA
ProteomicsA truncated and catalytically inactive form of KDM5B histone demethylase accumulates in breast cancer cells and regulates H3K4 tri-methylation and gene expression
KDM5B histone demethylase is overexpressed in many cancers with an ambivalent role in oncogenesis which depends on the specific contest. A putative explanation of this ambivalence could be represented by the expression pattern of different protein isoforms with different functional roles which could...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD033337 | Pride
Histone ptms Epigenetics Hmes 
GenomicsSwd2/Cps35 determines H3K4 tri-methylation via interactions with Set1 and Rad6_Chromatin occupancy of Set1 in several strains
Swd2/Cps35 determines H3K4 tri-methylation via interactions with Set1 and Rad6_Chromatin occupancy of Set1 in several strains
PRJNA982058 | ENA
ProteomicsBRWD3 targets KDM5/Lid for degradation to maintain H3K4 methylation levels
Histone modifications are critical for regulating chromatin structure and gene expression. Dysregulation of histone modification levels may contribute to disease development and cancer. Therefore, understanding histone modifications is essential for development and disease. The chromatin-binding pro...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2023-09-19 | PXD039706 | Pride
H3k4 Histone Degradation E3 ubiquitin ligase Brwd3 
UnknownDNA demethylation and tri-methylation of H3K4 at the TACSTD2 promoter are complementary players for TROP2 regulation in colorectal cancer cells.
Not available
S-EPMC10834991 | biostudies-literature
TranscriptomicsThe association between gene expression and whole genome histone H3K4 mono-, di, and trimethylation: expression data
These microarrays are part of a study where a comparison was made between the change in transcription and H3K4 mono-, di-, and tri-methylation levels (via ChIP-seq) in the Arabidopsis thaliana genome when plants are subjected to water deficit stress. Water deficit stress causes a large number of gen...
ORGANISM(S): Arabidopsis thaliana 
2010-12-07 | E-GEOD-11538 | biostudies-arrayexpress
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