Sort   by:  
 Page size 
MetabolomicsHistone H3K4me3 Demethylase RBP2 Transcriptionally Activates PPARγ to Drive Lipid Metabolic Reprogramming in Gastric Carcinoma

This work investigates epigenetic driven lipid metabolic reprogramming in gastric carcinoma. We characterize that histone H3K4me3 demethylase RBP2 transcriptionally activates PPARgama by binding to its promoter region,thereby promoting lipogenic gene expression and intracellular lipid accumulatio...

2026-08-14 | MTBLS15324 | MetaboLights
GenomicsGene specific signatures by H3K4me2 and H3K27me3 modifications during retina maturation
Control of neural organogenesis is a complex process and the epigenetic contribution is largely unknown. Here we have followed the genome-wide distribution of two important histone H3 modifications, H3K4me2 and H3K27me3 during late mouse retina development. We found that genes expressed only in matu...
ORGANISM(S): Mus musculus 
2012-12-13 | E-GEOD-38500 | biostudies-arrayexpress
ProteomicsH3K4me2 regulates the recovery of protein biosynthesis and homeostasis from UV-induced DNA damage during development and aging
DNA damage causes cancer, impairs development and accelerates aging. UV irradiation induces transcription-blocking lesions and defects in transcription-coupled nucleotide excision repair lead to developmental failure and premature aging in humans. Following DNA repair, the homeostatic processes need...
ORGANISM(S): Caenorhabditis elegans 
2020-10-13 | PXD015354 | Pride
Uv H3k4me2 C. elegans Dna damage 
GenomicsEpigenetic and transcriptional control in hematopoietic development and lineage differentiation
Hematopoiesis is a well-established model system to study molecular mechanisms of lineage-specific differentiation. Key transcription factors (TFs), such as PU.1, NF-E2 and GATA1 are implicated in crucial aspects of distinct hematopoietic lineages. How TFs collaborate with histone modificatons and h...
ORGANISM(S): Mus musculus 
2014-07-28 | E-GEOD-42110 | biostudies-arrayexpress
Transcriptomicsh3k4me2_gw-Establishing a reference epigenome in arabidopsis seedlings
gfe_epigenome - h3k4me2_gw - Epigenomic mapping - Epigenomic mapping of H3K4me2 4 dye-swap - chip-chip
ORGANISM(S): Arabidopsis thaliana 
2011-04-19 | E-GEOD-24659 | biostudies-arrayexpress
GenomicsH3K4me2 ChIP-seq upon GSK inhibiton
H3K4me2 ChIP-seq upon GSK inhibiton
PRJNA543247 | ENA
UnknownH3K4me2 orchestrates H2A.Z and Polycomb repressive marks in Arabidopsis.
Not available
S-EPMC12749604 | biostudies-literature
GenomicsImpact of nuclear Piwi elimination on chromatin state in Drosophila melanogaster ovaries
The piRNA-interacting Piwi protein is involved in transcriptional silencing of transposable elements in ovaries of D. melanogaster. Here we characterized the genome-wide effect of nuclear Piwi elimination on the presence of the heterochromatic H3K9me3 mark and HP1a, as well as on the transcription-a...
ORGANISM(S): Drosophila melanogaster 
2014-05-19 | E-GEOD-56347 | biostudies-arrayexpress
UnknownH3K4me2 functions as a repressive epigenetic mark in plants.
Not available
S-EPMC6604379 | biostudies-literature
GenomicsH3K4me2 profiling in OCI-Ly1 and OCI-Ly7 cell lines.
Define and compare H3K4me2 enrichment in OCI-Ly1 and OCI-Ly7 cell lines. Using ChIP-seq, we examined the H3K4me2 genomic enrichment locations in two biological replicates in each cell line
ORGANISM(S): Homo sapiens 
2015-08-28 | E-GEOD-67381 | biostudies-arrayexpress
Sort   by:  
 Page size