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TranscriptomicsTranscription profiling of fibroblast-like synovial cells from normal adult horse following treatment with hyaluronan and challenged with lipopolysaccharide
Greater than 95% confluent (Day 0) fibroblast-like synovial cells from the hind limbs (pelvic limb) of normal adult horses were allocated in triplicate to one of 4 groups:

(group 1) unchallenged;
(group 2) LPS-challenged;
(group 3) LPS-challenged following pre-treatment and susta...
ORGANISM(S): Equus caballus 
2007-01-10 | E-MEXP-940 | biostudies-arrayexpress
GenomicsGenome-wide binding analysis of GATA1fl and GATA1s in G1ME cells.
We used chromatin immunoprecipitation sequencing (ChIP-seq) to compare genome-wide binding profiles of GATA1fl and GATA1s in G1ME cells, which are immortalized, developmentally arrested megakaryocyte-erythroid progenitors (MEPs) derived from in vitro differentiation of murine Gata1- ES cells. Althou...
ORGANISM(S): Mus musculus 
2015-01-26 | E-GEOD-61932 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of amaygdala, cortex and hippocampus from rats subjected to immobilization stress
Prolonged stress has adverse consequences for neurons in the hippocampus (HIPP). The amygdala (AMY) is a brain region that is similar to HIPP across many measures, suggesting that chronic stress might modulate AMY and HIPP function in similar ways. However, studies addressing this issue have produce...
ORGANISM(S): Rattus norvegicus 
2007-07-31 | E-GEOD-2870 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling and ChIP-chip analyses of S. pombe strains exhibiting flocculation phenotype by overexpression and deletion
In the fission yeast Schizosaccharomyces pombe, the transcriptional-regulatory network that governs flocculation remains poorly understood. Here, we systematically screened an array of transcription factor deletion and overexpression strains for flocculation and performed microarray expression profi...
ORGANISM(S): Schizosaccharomyces pombe 
2012-11-02 | E-GEOD-41730 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human colon Caco-2 cells treated with sulforaphane (SF)
Effect of sulforaphane (SF) on human colon caco-2 cells after 24h treatment
ORGANISM(S): Homo sapiens 
2005-07-01 | E-MEXP-170 | biostudies-arrayexpress
UnknownCombined Microsatellite Instability, MLH1 Methylation Analysis, and Immunohistochemistry for Lynch Syndrome Screening in Endometrial Cancers From GOG210: An NRG Oncology and Gynecologic Oncology Group Study.
Not available
S-EPMC4678181 | biostudies-literature
TranscriptomicsExperimental identification of miR-378-3p targets by overexpression and silencing in murine NIH-3T3 fibroblasts
MicroRNAs (miRNAs) are short noncoding RNA molecules regulating the expression of mRNAs. Target identification of miRNAs is computationally difficult due to the relatively low homology between miRNAs and their targets. We provide data here utilizing an experimental approach to identify targets of mm...
ORGANISM(S): Mus musculus 
2012-08-07 | E-GEOD-34873 | biostudies-arrayexpress
UnknownGenome-wide diversity and selective pressure in the human rhinovirus.
Not available
S-EPMC1892812 | biostudies-literature
TranscriptomicsNIH/NIAID On the resistance of Staphylococcus aureus to neutrophil microbicides
Staphylococcus aureus strain MW2 was exposed to the following neutrophil microbicides, hydrogen peroxide (H2O2), hypochlorous acid (HOCl) and azurophilic granule proteins. At the indicated time points, bacterial cultures were centrifuged and bacteria were lysed with RLT buffer (Qiagen) using a Fast...
ORGANISM(S): Staphylococcus aureus 
2010-05-26 | E-GEOD-6716 | biostudies-arrayexpress
TranscriptomicsHMGA1: A master regulator of tumor progression in triple-negative breast cancer cells
Emerging evidence suggests that tumor cells metastasize by co-opting stem cell transcriptional networks, although the molecular underpinnings of this process are poorly understood. Here, we show for the first time that the high mobility group A1 (HMGA1) gene drives metastatic progression in triple ...
ORGANISM(S): Homo sapiens 
2015-02-18 | E-GEOD-45483 | biostudies-arrayexpress
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