Pathogen-derived peptides presented by MHCII that are best able to activate cognate CD4+ T cells and initiate an adaptive immune response are termed immunodominant. The exact mechanisms and molecular determinants of antigen processing that contribute to immunodominance remain unclear. Recently, atte...
ORGANISM(S): Influenza A virus (A/New Caledonia/20-JY2/1999(H1N1))
Immunopeptidomics of pancreatic beta cells and detection of peptide sequences from canonical and novel open reading frames and aberant translation events.