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ProteomicsProteomic Genotyping: Using Mass Spectrometry to Infer SNP Genotypes in Pigmented and Non-Pigmented Hair
Proteomic genotyping is the use of genetically variant peptides (GVPs), detected in a forensic protein sample, to infer the genotype of corresponding non-synonymous SNP alleles in the donor’s genome. This process does not depend on the presence of accessible or useable DNA in a sample. This makes pr...
ORGANISM(S): Homo sapiens (Human) 
2020-05-27 | PXD016156 | Pride
Proteomic genotyping Hair Hair pigmentation Melanosomes Genetically variant peptides 
ProteomicsProfiling Protein Expression Levels and Genetically Variant Peptides in Human Hair From Different Body Sites
Proteins of the human hair shaft contain a wealth of information about the coding regions of the person’s genome from whom the hair is derived. Commonly found at crime scenes, hair shafts may thus provide useful forensic evidence if the information they contain can be exploited. Present experiments ...
ORGANISM(S): Homo sapiens (Human) 
2019-04-04 | PXD011732 | Pride
Protein profiling Hair shafts Genetically variant peptides Human identification 
ProteomicsIdentification and Characterisation of Taxonomically Informative Peptides
Hair fibers serve as a prevalent and valuable form of biological trace evidence. Taxonomic classification of hair recovered during a criminal investigation provides crucial forensic intelligence and aids in evidence prioritisation. Traditional classification methods rely heavily on the analysis of h...
ORGANISM(S): Mus musculus (Mouse) Vulpes vulpes (Red fox) Sus scrofa domesticus (domestic pig) Ovis aries Bos taurus (Bovine) Camelus dromedarius (Dromedary) (Arabian camel) Vicugna pacos Homo sapiens (Human) Oryctolagus cuniculus (Rabbit) Felis catus (Cat) (Felis silvestris catus) Canis familiaris (Dog) (Canis lupus familiaris) Cavia porcellus (Guinea pig) Rattus norvegicus (Rat) Capra hircus (Goat) Equus caballus (Horse) 
2026-05-13 | PXD062555 | Pride
Hrms Discovery proteomics Taxonomic classification 
ProteomicsIDENTIFICATION AND CHARACTERISATION OF TAXONOMICALLY INFORMATIVE PEPTIDES BY HIGH RESOLUTION MASS SPECTROMETRY FOR SOURCE IDENTIFICATION OF TRACE HAIR
In this study a proteomics workflow was developed for the discovery and characterization of taxonomically diagnostic hair peptides. Taxa were selected with a focus on relevance to crime scene investigation. A panel of 226 taxonomically informative peptides were identified and characterized, 209 whic...
ORGANISM(S): Bos taurus (Bovine) Sus scrofa (Pig) Camelus dromedarius (Dromedary) (Arabian camel) Vicugna pacos Mus musculus (Mouse) Homo sapiens (Human) Canis lupus Oryctolagus cuniculus (Rabbit) Felis catus (Cat) (Felis silvestris catus) Cavia porcellus (Guinea pig) Rattus norvegicus (Rat) Equus caballus (Horse) 
2026-05-13 | PXD065721 | Pride
Taxonomically informative biomarkers Hair proteins Forensic proteomics Trace evidience 
Genomics
Historical hair shafts sequencing
PRJNA782999 | ENA
ProteomicsAutophagy controls the protein composition of hair shafts
Hair shafts are formed by terminal differentiation of hair keratinocytes (trichocytes) in which keratins and keratin-associated proteins accumulate and undergo cross-linking. Here we tested the hypothesis that maturation of the hair shaft also involves the coordinated degradation of other proteins a...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-01-17 | MSV000091072 | MassIVE
ProteomicsBald thigh syndrome in sighthounds
Bald thigh syndrome is a common hair loss disorder in sighthounds. The overall goal of our study was to identify the cause of bald thigh syndrome and the pathological changes associated with it. We approached this aim by comparing skin biopsies and hair shafts of affected and control dogs microscopi...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2019-11-13 | PXD012371 | Pride
Hair Greyhound dog Bald thigh syndrome Proteome 
UnknownTrichothiodystrophy hair shafts display distinct ultrastructural features.
Not available
S-EPMC10575343 | biostudies-literature
UnknownBacteria Display Differential Growth and Adhesion Characteristics on Human Hair Shafts.
Not available
S-EPMC6137140 | biostudies-literature
ProteomicsAlternative LC-MS/MS Platforms and Data Acquisition Strategies for Proteomic Genotyping
Protein is a major component of all biological evidence. Proteomic genotyping is the use of genetically variant peptides that contain single amino acid polymorphisms to infer the genotype of matching non-synonymous single nucleotide polymorphisms for the individual who originated the protein sample....
ORGANISM(S): Homo Sapiens 
2021-09-10 | PXD024651 | panorama
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