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ProteomicsTMEM260 is a protein-specific O-mannosyltransferase
Mutations in the TMEM260 gene cause structural heart defects and renal anomalies syndrome (SHDRA), but the function of the encoded protein remains unknown. We report that TMEM260 is an ER-located protein O-mannosyltransferase that selectively glycosylates defined extracellular immunoglobulin, plexin...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2023-05-05 | PXD032328 | Pride
O-mannosylation Glycoproteomics Glycopeptide Tmem260 
ProteomicsA Bacterial Mannose Binding Lectin as a Tool for the Enrichment of C-and O- Mannosylated Peptides
C-mannosylated peptides are easily detected by mass spectrometry (MS) from purified proteins but not from complex biological samples. Enrichment of specific glycopeptides by lectin affinity prior to MS analysis has been widely applied to support glycopeptide identification, but was up till now not a...
ORGANISM(S): Homo sapiens (Human) 
2022-05-13 | PXD031355 | Pride
Etcid Bc2l-a lectin Glycoproteomics O-mannosylation C-mannosylation 
ProteomicsNucleocytoplasmic O-Man glycoproteome
Dynamic cycling of N-Acetylglucosamine (GlcNAc) on serine (Ser) and threonine (Thr) residues (O-GlcNAcylation) is an essential process in all eukaryotic cells except yeast, e.g Saccharomyces cerevisiae. O-GlcNAcylation modulates signaling and cellular processes in an intricate interplay with protein...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) Schizosaccharomyces pombe 
2015-12-08 | PXD002924 | Pride
O-glycoproteomics Saccharomyces cerevisiae 
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Not available
S-EPMC7686114 | biostudies-literature
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UnknownStructure and dynamics of membrane protein in SARS-CoV-2.
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UnknownGreen micellar UPLC and complementary eco-friendly spectroscopic techniques for simultaneous analysis of anti-COVID drugs: a comprehensive evaluation of greenness, blueness, and whiteness.
Not available
S-EPMC11312741 | biostudies-literature
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